Tetramethylpyrazine

Basic Information

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CAS Number

1124-11-4

Molecular Formula

C8H12N2

Molecular Weight

136.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

77-80 °C

Boiling Point

190 °C

Water Solubility

Soluble in water (4 g/L at 20°C).

Flash Point

128-130℃/200mm

Solubility

4g/l

Refractive Index

1.5880 (estimate)

SMILES

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Cc1nc(C)c(C)nc1C

InChI

InChI=1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3

InChIKey

FINHMKGKINIASC-UHFFFAOYSA-N

LogP

1.7102799999999998

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

87.8

Safety Information

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GHS Hazard Pictograms

H302

H315

H318

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Storage Conditions

2-8℃

Stability

Stable. Incompatible with strong acids and strong oxidizers.

Synonyms & References

English

2,3,5,6-Tetramethylpyrazine
BS Factor
Ligustrazine
Pyrazine,tetramethyl-
Tetramethylpyrazin
tetramethyl-pyrazin
2,3,5,6-TETRAMETHYLPYRAZINES
2,3,5,6-TETRAMETHYL-1,4-PYRAZINE
Tetramethylpyrazine
2.3.5.6-Tetramethyl Pyrazine
Ligustrazine, Tetramethylpyrazine
TETRAMETHYLPYRAZINE, 2,3,5,6-(P)
2,3,5,6-Tetramethyl pyrazine
Pyrazine, tetramethyl-
Tetrapyrazine
Liqustrazine
Chuanxiongzine
Ligustizine
TMPZ
FEMA No. 3237
2,3,5,6,-Tetramethyl-1,4-pyrazine
V80F4IA5XG
2,3,5,6-Tetramethylpyrazine (natural)
MLS000069594
FEMA 3237
FINHMKGKINIASC-UHFFFAOYSA-N
Pyrazine, 2,3,5,6-tetramethyl-
SMR000059042
2,5,6-Tetramethylpyrazine
chuan
2,3,5,6-tetramethypyrazine（3H2O）

MDL Number

MFCD00006146

Customs Code

29339990

FAQ

What is Tetramethylpyrazine (CAS: 1124-11-4)?

Tetramethylpyrazine is a synthetic organic compound with the chemical formula C6H10N2. It is a colorless liquid with a distinct, often described as garlic-like, odor. This compound is known for its pharmacological properties, including potential effects on the central nervous system and cardiovascular system. It is commonly used in the pharmaceutical and food industries due to its unique characteristics.

What are the main uses of Tetramethylpyrazine (CAS: 1124-11-4)?

Tetramethylpyrazine is primarily used in pharmaceuticals for its potential therapeutic effects, such as improving blood circulation and reducing oxidative stress. It also finds applications in the food industry as a flavor enhancer and in research for studying its biological activities. Additionally, it is used in the production of certain perfumes and as a chemical intermediate in various industrial processes.

Is Tetramethylpyrazine (CAS: 1124-11-4) safe?

Tetramethylpyrazine is generally considered safe when used in appropriate amounts and under controlled conditions. However, it should be handled with care, as inhalation or prolonged skin contact may cause irritation. Safety standards recommend proper ventilation and the use of protective gloves and goggles. It is important to follow guidelines for safe handling and storage to minimize potential risks.

How should Tetramethylpyrazine (CAS: 1124-11-4) be stored?

Tetramethylpyrazine should be stored in a cool, dry, and well-ventilated area away from direct light. It is recommended to keep it in a sealed, airtight container at a temperature below 25°C and humidity levels below 60%. Proper storage ensures stability and prevents degradation, maintaining its quality and effectiveness for use in various applications.