(2S)-2-Amino-3,3-dimethyl-1-butanol

Basic Information

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CAS Number

112245-13-3

Molecular Formula

C6H15NO

Molecular Weight

117.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

30-34 °C

Boiling Point

130°C/32mmHg

Refractive Index

38 ° (C=1.5, EtOH)

Specific Rotation

+33-40° (c=1.5, EtOH)

SMILES

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CC(C)(C)C(CO)N

InChI

InChI=1S/C6H15NO/c1-6(2,3)5(7)4-8/h5,8H,4,7H2,1-3H3/t5-/m1/s1

InChIKey

JBULSURVMXPBNA-RXMQYKEDSA-N

LogP

0.35210000000000025

Topological Polar Surface Area

46.25 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

65.4

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

CS-W005274
(L)-tert-Leucinol
STL557486
112245-13-3
L-tert Leucinol
H-Tle-ol
EN300-91735
L-t-leucinol
(2s)-2-amino-3,3-dimethyl-1-butanol
AC-35147
CHEMBL4525330
L-tert-Leucinol
(S)-2-amino-3
tert-leucinol
Q-101657
L-tert-Leucinol, 98%
BP-12907
(S)-2-Amino-3,3-dimethyl-1-hydroxybutane
BBL103676
MFCD00192250
SCHEMBL477841
AKOS015841184
(s)-t-leucinol
DTXSID50920704
AKOS006341646
L0160
JBULSURVMXPBNA-RXMQYKEDSA-N
Q-201329
L-tert -leucinol
(2S)-2-amino-3,3-dimethylbutan-1-ol
s-tert-leucinol

MDL Number

MFCD00192250

FAQ

What are the physical and chemical properties of (2S)-2-Amino-3,3-dimethyl-1-butanol (CAS: 112245-13-3)?

(2S)-2-Amino-3,3-dimethyl-1-butanol (CAS: 112245-13-3) is a colorless liquid with a molecular weight of approximately 132.2 g/mol. It has a distinct odor and is slightly soluble in water. The compound is known for its reactivity, particularly towards nucleophiles at the amino group. It has a melting point of -10°C and boiling point of 120°C. This compound is used in various applications due to its unique chemical properties.

How is (2S)-2-Amino-3,3-dimethyl-1-butanol (CAS: 112245-13-3) typically synthesized?

(2S)-2-Amino-3,3-dimethyl-1-butanol (CAS: 112245-13-3) can be synthesized through a multi-step process involving the reduction of 2,3,3-trimethyl-1-butanone with sodium borohydride, followed by the amination of the resulting alcohol. This process yields a high yield of the desired product with good selectivity. The reaction conditions are carefully controlled to ensure the purity and quality of the final product.

What industries use (2S)-2-Amino-3,3-dimethyl-1-butanol (CAS: 112245-13-3)?

(2S)-2-Amino-3,3-dimethyl-1-butanol (CAS: 112245-13-3) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It is also used in the production of certain sensors and as a precursor in the development of new materials. Its unique chemical properties make it a valuable compound in research and industrial applications.

What precautions should be taken when handling (2S)-2-Amino-3,3-dimethyl-1-butanol (CAS: 112245-13-3)?

When handling (2S)-2-Amino-3,3-dimethyl-1-butanol (CAS: 112245-13-3), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. This compound is flammable and may cause skin or eye irritation. It should be stored in a cool, well-ventilated area away from heat sources and strong oxidizers. In the event of a spill, immediately evacuate the area and follow emergency procedures outlined in the Safety Data Sheet (SDS).