1-Chloro-2-[2-(2-chloroethoxy)ethoxy]ethane

Basic Information

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CAS Number

112-26-5

Molecular Formula

C6H12Cl2O2

Molecular Weight

187.07 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Melting Point

-31°C

Boiling Point

235 °C

Solubility

insoluble

Refractive Index

n20/D 1.461(lit.)

SMILES

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C(COCCCl)OCCCl

InChI

InChI=1S/C6H12Cl2O2/c7-1-3-9-5-6-10-4-2-8/h1-6H2

InChIKey

AGYUOJIYYGGHKV-UHFFFAOYSA-N

LogP

1.4971999999999999

Topological Polar Surface Area

18.46 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

53.7

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

DTXSID8047000
Ethylene Glycol Bis(2-chloroethyl) Ether
AI3-28584
Triethylene glycol dichloride
EN300-19706
Ethane, 1,2-bis(2-chloroethoxy)-
J-002738
E76650
AKOS009031431
1,2-BIS(2-CHLOROETHOXY)ETHANE [HSDB]
Bis(chloroethoxy)ethane
1-Chloro-2-[2-(2-chloroethoxy)ethoxy]ethane
HSDB 5400
112-26-5
UNII-28JQ82M13J
Q27254323
Di(2-chloroethyl) Cellosolve
AMY9371
NS00006522
InChI=1/C6H12Cl2O2/c7-1-3-9-5-6-10-4-2-8/h1-6H2
1,2-bis-(2-Chloroethoxy)ethane
1,8-dichloro-3, 6-dioxaoctane
A802531
AGYUOJIYYGGHKV-UHFFFAOYSA-
Triglycol dichloride
Tox21_302011
CAS-112-26-5
1,2-bis-(2-chloro-ethoxy)-ethane
CHEMBL3188977
MFCD00000976
BRN 0506177

MDL Number

MFCD00000976

Customs Code

29091900

FAQ

What are the physical and chemical properties of 1-Chloro-2-[2-(2-chloroethoxy)ethoxy]ethane (CAS: 112-26-5)?

1-Chloro-2-[2-(2-chloroethoxy)ethoxy]ethane (CAS: 112-26-5) is a colorless, viscous liquid with a high boiling point and low volatility. Its molecular weight is approximately 314.02 g/mol. This compound has limited water solubility but is miscible with organic solvents. It is moderately reactive, particularly towards nucleophiles and bases. It is used in various applications due to its unique chemical structure.

How is 1-Chloro-2-[2-(2-chloroethoxy)ethoxy]ethane (CAS: 112-26-5) typically synthesized?

1-Chloro-2-[2-(2-chloroethoxy)ethoxy]ethane (CAS: 112-26-5) is synthesized via a series of chlorination and etherification reactions. The key steps involve the chlorination of ethylene glycol followed by an etherification reaction to form the desired product. This process typically requires mild to moderate reaction conditions and the use of appropriate catalysts to ensure high selectivity and yield.

What industries use 1-Chloro-2-[2-(2-chloroethoxy)ethoxy]ethane (CAS: 112-26-5)?

1-Chloro-2-[2-(2-chloroethoxy)ethoxy]ethane (CAS: 112-26-5) is primarily used in the pharmaceutical, polymer, and chemical industries. It serves as a key intermediate in the synthesis of various pharmaceuticals and is also used as a building block in polymer synthesis for specific properties. Additionally, it finds applications in sensor technology and semiconductor manufacturing due to its unique chemical structure.

What precautions should be taken when handling 1-Chloro-2-[2-(2-chloroethoxy)ethoxy]ethane (CAS: 112-26-5)?

When handling 1-Chloro-2-[2-(2-chloroethoxy)ethoxy]ethane (CAS: 112-26-5), it is crucial to wear proper personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Ensure that the work is conducted in a well-ventilated area or a fume hood to avoid inhalation of fumes. Spills should be cleaned up promptly with appropriate absorbent materials, and the area should be well-ventilated. Refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.