Erythromycin A Oxime

Basic Information

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CAS Number

111321-02-9

Molecular Formula

C37H68N2O13

Molecular Weight

748.95 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

178-180 ºC

SMILES

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CCC1C(C(C(C(=NO)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O

InChI

InChI=1S/C37H68N2O13/c1-14-25-37(10,45)30(41)20(4)27(38-46)18(2)16-35(8,44)32(52-34-28(40)24(39(11)12)15-19(3)48-34)21(5)29(22(6)33(43)50-25)51-26-17-36(9,47-13)31(42)23(7)49-26/h18-26,28-32,34,40-42,44-46H,14-17H2,1-13H3/b38-27+/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1

InChIKey

KYTWXIARANQMCA-ZTILBQITSA-N

LogP

2.0467000000000035

Topological Polar Surface Area

209.42999999999998 Å²

Hydrogen Bond Donor/Acceptor

6 / 15

Complexity

1210

Synonyms & References

English

Erythromycin-9-oxime
Erythromycin A oxime
MFCD08062410
NS00077329
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one
Erythromycin Impurity J
SCHEMBL13615734
13127-18-9
J-005969
111321-02-9
Erythromycin oxime
Roxithromycin Impurity C
Erythromycin, 9-oxime,(9E)- (9CI)
Erythromycin A Oxime
(9E)-Erythromycin A Oxime
(E)-Erythromycin oxime
ERYTHROMYCIN OXIME BASE
(E)-Erythromycin A oxime
Oxacyclotetradecane,erythromycin deriv.
Azithromycin Impurity S ((9E)-Erythromycin A Oxime)
Roxithromycin EP Impurity C (Erythromycin Impurity J)
(9E)-Erythromycin A Oxime Roxithromycin EP Impurity C
(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(hydroxyimino)-3,5,7,9
(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(hydroxyimino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one

MDL Number

MFCD08062410

FAQ

What regulatory guidelines apply to Erythromycin A Oxime (CAS: 111321-02-9)?

Erythromycin A Oxime (CAS: 111321-02-9) is subject to various regulatory guidelines, including the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH regulations for substances above one tonne per year, and FDA/EPA requirements for pharmaceutical and environmental safety. Manufacturers and distributors must ensure compliance with these regulations to handle, label, and transport the compound safely.

Are there alternatives to Erythromycin A Oxime (CAS: 111321-02-9) in synthesis?

Yes, there are alternatives to Erythromycin A Oxime (CAS: 111321-02-9) in synthesis. Analogues such as Erythromycin A and other oxime derivatives can be used as substitutes. Common alternative reagents include hydroxylamine and hydrazine, which can be employed to generate related oxime compounds.

What is the market or research trend for Erythromycin A Oxime (CAS: 111321-02-9)?

The market and research trends for Erythromycin A Oxime (CAS: 111321-02-9) are focused on its antimicrobial properties and its role in developing new antibiotic treatments. Research is ongoing to explore its potential in combination therapies and to address the growing issue of antibiotic resistance. Market trends indicate increasing demand in the pharmaceutical industry, particularly in the treatment of respiratory infections and other bacterial infections.

How should waste containing Erythromycin A Oxime (CAS: 111321-02-9) be handled?

Waste containing Erythromycin A Oxime (CAS: 111321-02-9) should be handled with care to prevent environmental contamination and ensure safety. Collection should be done in appropriate containers, and the waste should be treated by incineration or professional waste disposal services. Environmental protection precautions include ensuring no leakage and proper labeling of waste containers to comply with regulatory requirements. Safe disposal is critical to avoid adverse effects on human health and the environment.