Recombinant insulin Human | CAS No. 11061-68-0

Q: What regulatory guidelines apply to Recombinant insulin Human (CAS: 11061-68-0)?

Recombinant insulin human (CAS: 11061-68-0) is subject to strict regulatory guidelines, including GHS classification for hazardous chemicals, REACH regulations for the European market, and FDA and EPA requirements for clinical and commercial use in the U.S. It must undergo rigorous safety and efficacy testing before approval and ongoing compliance with pharmacovigilance standards.

Q: Are there alternatives to Recombinant insulin Human (CAS: 11061-68-0) in synthesis?

Alternatives to recombinant insulin human (CAS: 11061-68-0) in synthesis include analogs like insulin glargine and lispro, which have modified structures for improved efficacy. Common alternative reagents include different expression systems, such as yeast or insect cells, and other biotechnological approaches for protein production.

Q: What is the market or research trend for Recombinant insulin Human (CAS: 11061-68-0)?

The market for recombinant insulin human (CAS: 11061-68-0) is driven by increasing diabetes prevalence and advanced biopharmaceutical technologies. Research trends focus on insulin analogs, long-acting formulations, and personalized medicine. Market trends show steady growth with a focus on reducing side effects and improving patient outcomes.

Q: How should waste containing Recombinant insulin Human (CAS: 11061-68-0) be handled?

Waste containing recombinant insulin human (CAS: 11061-68-0) should be collected in appropriate containers and disposed of through professional waste disposal services. Proper incineration or chemical treatment is necessary to ensure safety and meet regulatory requirements. Environmental protection measures, such as minimizing the release of hazardous substances, must also be followed to prevent contamination of water and soil.

Recombinant insulin Human

Basic Information

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CAS Number

11061-68-0

Molecular Formula

C257H383N65O77S6

Molecular Weight

5808 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Water Solubility

Soluble up to 10mg/ml in pH <3 or in the presence of surfactants. Adjusting pH with a volatile acid (such as formic acid) prior to dry down will allow the product to be re-dissolved in water.

Solubility

acidified water, pH 2.0: 2 mg/mL

SMILES

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CCC(C)C1C(=O)NC2CSSCC(C(=O)NC(CSSCC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CO)CC(C)C)CC3=CC=C(C=C3)O)CCC(=O)N)CC(C)C)CCC(=O)O)CC(=O)N)CC4=CC=C(C=C4)O)C(=O)NC(CC(=O)N)C(=O)O)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CC5=CC=CC=C5)C(=O)NC(CC6=CC=CC=C6)C(=O)NC(CC7=CC=C(C=C7)O)C(=O)NC(C(C)O)C(=O)N8CCCC8C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)O)C(C)C)CC(C)C)CC9=CC=C(C=C9)O)CC(C)C)C)CCC(=O)O)C(C)C)CC(C)C)CC2=CNC=N2)CO)NC(=O)C(CC(C)C)NC(=O)C(CC2=CNC=N2)NC(=O)C(CCC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(C(C)C)NC(=O)C(CC2=CC=CC=C2)N)C(=O)NC(C(=O)NC(C(=O)N1)CO)C(C)O)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C(C(C)CC)NC(=O)CN

InChI

InChI=1S/C257H383N65O77S6/c1-29-131(23)205(313-193(339)104-259)252(393)317-204(130(21)22)248(389)288-159(75-82-200(349)350)217(358)282-156(71-78-189(263)335)221(362)308-183-116-403-404-117-184-243(384)305-178(111-324)240(381)294-162(88-123(7)8)225(366)295-168(95-140-53-61-146(329)62-54-140)228(369)283-154(69-76-187(261)333)218(359)290-161(87-122(5)6)223(364)285-158(74-81-199(347)348)220(361)302-174(101-190(264)336)235(376)298-170(97-142-57-65-148(331)66-58-142)231(372)309-182(242(383)304-176(255(396)397)103-192(266)338)115-402-401-114-181(214(355)273-107-194(340)278-153(72-79-197(343)344)216(357)281-151(51-42-84-271-257(267)268)212(353)272-108-195(341)279-166(93-138-46-36-32-37-47-138)227(368)297-167(94-139-48-38-33-39-49-139)230(371)299-171(98-143-59-67-149(332)68-60-143)238(379)320-208(135(27)327)254(395)322-85-43-52-186(322)246(387)286-152(50-40-41-83-258)222(363)321-209(136(28)328)256(398)399)311-250(391)203(129(19)20)316-236(377)164(90-125(11)12)292-229(370)169(96-141-55-63-147(330)64-56-141)296-224(365)160(86-121(3)4)289-210(351)133(25)277-215(356)157(73-80-198(345)346)287-247(388)202(128(17)18)315-237(378)165(91-126(13)14)293-233(374)173(100-145-106-270-120-276-145)301-239(380)177(110-323)280-196(342)109-274-213(354)180(113-400-405-118-185(310-244(183)385)245(386)319-207(134(26)326)253(394)306-179(112-325)241(382)318-206(132(24)30-2)251(392)312-184)307-226(367)163(89-124(9)10)291-232(373)172(99-144-105-269-119-275-144)300-219(360)155(70-77-188(262)334)284-234(375)175(102-191(265)337)303-249(390)201(127(15)16)314-211(352)150(260)92-137-44-34-31-35-45-137/h31-39,44-49,53-68,105-106,119-136,150-186,201-209,323-332H,29-30,40-43,50-52,69-104,107-118,258-260H2,1-28H3,(H2,261,333)(H2,262,334)(H2,263,335)(H2,264,336)(H2,265,337)(H2,266,338)(H,269,275)(H,270,276)(H,272,353)(H,273,355)(H,274,354)(H,277,356)(H,278,340)(H,279,341)(H,280,342)(H,281,357)(H,282,358)(H,283,369)(H,284,375)(H,285,364)(H,286,387)(H,287,388)(H,288,389)(H,289,351)(H,290,359)(H,291,373)(H,292,370)(H,293,374)(H,294,381)(H,295,366)(H,296,365)(H,297,368)(H,298,376)(H,299,371)(H,300,360)(H,301,380)(H,302,361)(H,303,390)(H,304,383)(H,305,384)(H,306,394)(H,307,367)(H,308,362)(H,309,372)(H,310,385)(H,311,391)(H,312,392)(H,313,339)(H,314,352)(H,315,378)(H,316,377)(H,317,393)(H,318,382)(H,319,386)(H,320,379)(H,321,363)(H,343,344)(H,345,346)(H,347,348)(H,349,350)(H,396,397)(H,398,399)(H4,267,268,271)

InChIKey

PBGKTOXHQIOBKM-UHFFFAOYSA-N

LogP

-19.37233000000035

Topological Polar Surface Area

2299.0700000000006 Å²

Hydrogen Bond Donor/Acceptor

88 / 142

Complexity

14600

Synonyms & References

English

11061-68-0
Recombinant insulin Human
Insulin (human)
Recombinant Human Insulin
Human Insulin, Solution
Insulin
Insulin (human) recombinant
Insulin, huMan
Insulin, recoMbinant huMan, Min. 27.5 IU
Insulin, Zinc, Human, Recomb.
rh-Insulin
ORMD 0801
Oral-lyn
Penfil R
Ultraphane
Umulin
Velosulin HM
D03230
novolin
Humulin
humuline
velosulin

MDL Number

MFCD00131380

FAQ

What regulatory guidelines apply to Recombinant insulin Human (CAS: 11061-68-0)?

Recombinant insulin human (CAS: 11061-68-0) is subject to strict regulatory guidelines, including GHS classification for hazardous chemicals, REACH regulations for the European market, and FDA and EPA requirements for clinical and commercial use in the U.S. It must undergo rigorous safety and efficacy testing before approval and ongoing compliance with pharmacovigilance standards.

Are there alternatives to Recombinant insulin Human (CAS: 11061-68-0) in synthesis?

Alternatives to recombinant insulin human (CAS: 11061-68-0) in synthesis include analogs like insulin glargine and lispro, which have modified structures for improved efficacy. Common alternative reagents include different expression systems, such as yeast or insect cells, and other biotechnological approaches for protein production.

What is the market or research trend for Recombinant insulin Human (CAS: 11061-68-0)?

The market for recombinant insulin human (CAS: 11061-68-0) is driven by increasing diabetes prevalence and advanced biopharmaceutical technologies. Research trends focus on insulin analogs, long-acting formulations, and personalized medicine. Market trends show steady growth with a focus on reducing side effects and improving patient outcomes.

How should waste containing Recombinant insulin Human (CAS: 11061-68-0) be handled?

Waste containing recombinant insulin human (CAS: 11061-68-0) should be collected in appropriate containers and disposed of through professional waste disposal services. Proper incineration or chemical treatment is necessary to ensure safety and meet regulatory requirements. Environmental protection measures, such as minimizing the release of hazardous substances, must also be followed to prevent contamination of water and soil.