Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide | CAS No. 1105067-87-5

Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide

Basic Information

CAS Number

1105067-87-5

Molecular Formula

C40H45FN3O10-

Molecular Weight

746.81 g/mol

AD

Basic Physical Properties

CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)NCCC(CC(CC(=O)[O-])O)O)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)NCCC(CC(CC(=O)[O-])O)O)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.[Ca+2]

InChI

InChI=1S/C40H46FN3O10/c1-23(2)36-35(40(54)44(27-11-7-4-8-12-27)38(39(42)53)31(48)20-30(47)22-33(51)52)34(24-9-5-3-6-10-24)37(25-13-15-26(41)16-14-25)43(36)18-17-28(45)19-29(46)21-32(49)50/h3-16,23,28-31,38,45-48H,17-22H2,1-2H3,(H2,42,53)(H,49,50)(H,51,52)/p-1/t28-,29-,30?,31?,38?/m1/s1

InChIKey

KVDHARMPHWCHQG-ZZHXZDKKSA-M

LogP

2.8139000000000003

Topological Polar Surface Area

226.67999999999998 Ų

Hydrogen Bond Donor/Acceptor

7 / 13

Complexity

1090

Synonyms & References

English

  • Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide
  • calcium,(3R,5R)-7-[[(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoyl]amino]-3,5-dihydroxyheptanoate
  • Atorvastatin EP Imp F
  • (3R,5R)-7-[[(3R,5R)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-heptanoic Acid Calcium Salt
  • Calcium bis[(3R,5R)-7-({(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoyl}amino)-3,5-dihydroxyheptanoate]
  • 1105067-87-5
  • calcium;(3R,5R)-7-[[(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoyl]amino]-3,5-dihydroxyheptanoate
  • DTXSID70747056

FAQ

What regulatory guidelines apply to Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide (CAS: 1105067-87-5)?

Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide (CAS: 1105067-87-5) falls under regulatory guidelines such as the REACH regulations for chemical substances, FDA requirements for pharmaceuticals, and EPA guidelines for environmental handling. These regulations cover safety data sheets, risk assessment, and proper disposal methods.

Are there alternatives to Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide (CAS: 1105067-87-5) in synthesis?

Synthetic alternatives to Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide include similar statins like Simvastatin or Pravastatin. Alternative reagents and processes can also be used in synthesis, but they may require different handling and regulatory considerations.

What is the market or research trend for Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide (CAS: 1105067-87-5)?

Research trends for Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide (CAS: 1105067-87-5) are focusing on improving its efficacy and exploring its potential in combination therapies. Market-wise, there is a growing interest in cost-effectiveness and sustainability, driven by increasing awareness of cardiovascular diseases.

How should waste containing Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide (CAS: 1105067-87-5) be handled?

Waste containing Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide (CAS: 1105067-87-5) should be collected in sealed containers and disposed of through professional waste disposal services. Proper incineration and environmental protection measures should be taken to ensure compliance with regulatory guidelines.

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