Paroxetine hydrochloride hemihydrate

Basic Information

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CAS Number

110429-35-1

Molecular Formula

C38H44Cl2F2N2O7

Molecular Weight

749.7 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

No data available

Melting Point

121-131 C

Boiling Point

451.7°C at N/A mmHg

Density

1.0500

Flash Point

No data available

Solubility

Soluble in DMSO (25 mg/ml), chloroform, and methanol. Insoluble in water

Vapor Pressure

No data available

SMILES

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C1CNCC(C1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.C1CNCC(C1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.O.Cl.Cl

InChI

InChI=1S/2C19H20FNO3.2ClH.H2O/c2*20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;;;/h2*1-6,9,14,17,21H,7-8,10-12H2;2*1H;1H2/t2*14-,17-;;;/m00.../s1

InChIKey

MQZOATSIFWSKKT-OASXIEIISA-N

LogP

4.45730

Complexity

402

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 9 Class 9

Synonyms & References

English

Paroxetine.HCl.hemihydrate
D02260
(-)-trans-4-(4-Fluorophenyl)-3-(3,4-methylenedioxyphenoxymethyl)piperidine hydrochloride hemihydrate
PAROXETINE HYDROCHLORIDE HEMIHYDRATE [MI]
X2ELS050D8
Paroxetine.HCl.hemihydrate, 1mg/ml in Methanol
(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidin-1-ium;chloride
Paroxetine hydrochloride hemihydrate
(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine;hydrate;dihydrochloride
Paxil
PAROXETINE HYDROCHLORIDE HEMIHYDRATE [WHO-DD]
(3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidinehydrochloridehemihydrate
Q27293431
PAROXETINE HYDROCHLORIDE HEMIHYDRATE [EP MONOGRAPH]
PAROXETINE HYDROCHLORIDE [ORANGE BOOK]
Paroxetine hydrochloride hydrate (JP17)
NCGC00181791-01
AC-16708
PAROXETINE HYDROCHLORIDE HYDRATE [JAN]
KS-1094
110429-35-1
Paroxetine hydrochloride hemihydrate (USP)
PAROXETINE HYDROCHLORIDE HEMIHYDRATE [USP MONOGRAPH]
Paroxetine Hydrochloride Hemihydrate 1.0 mg/ml in Methanol (as anhydrous free base)
(3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine hydrochloride hemihydrate
DTXSID101017095
Paroxetine HCl hydrate
AKOS015962357
(-)-(3S,4R)-4-(P-FLUOROPHENYL)-3-((3,4-METHYLENEDIOXY)PHENOXY)-METHYL)PIPERIDINE HYDROCHLORIDE HEMIHYDRATE
UNII-X2ELS050D8
PAROXETINE HYDROCHLORIDE [USP-RS]

MDL Number

MFCD03658863

Customs Code

2934999090

FAQ

What is Paroxetine hydrochloride hemihydrate (CAS: 110429-35-1)?

Paroxetine hydrochloride hemihydrate is a pharmaceutical compound with the CAS number 110429-35-1. It is a salt form of the antidepressant paroxetine, containing one mole of hydrochloric acid and one-half mole of water. It is a white crystalline powder with a bitter taste and hygroscopic nature.

What are the main uses of Paroxetine hydrochloride hemihydrate (CAS: 110429-35-1)?

Paroxetine hydrochloride hemihydrate is primarily used as an antidepressant and for the treatment of anxiety disorders. It is also prescribed for obsessive-compulsive disorder, panic disorder, and premenstrual dysphoric disorder. This compound is used in the pharmaceutical industry to produce medications for psychiatric conditions.

Is Paroxetine hydrochloride hemihydrate (CAS: 110429-35-1) safe?

Paroxetine hydrochloride hemihydrate is generally considered safe when used as directed by a healthcare provider. However, it may cause side effects such as dizziness, nausea, and insomnia. It is important to follow the prescribed dosage and consult a doctor if any adverse reactions occur. Protective measures include avoiding alcohol and other central nervous system depressants to minimize side effects.

How should Paroxetine hydrochloride hemihydrate (CAS: 110429-35-1) be stored?

Paroxetine hydrochloride hemihydrate should be stored in a tightly closed container at room temperature (15-30°C or 59-86°F). It should be kept away from moisture and protected from light. Avoid storing it in humid areas or near heat sources to prevent degradation and maintain its stability. The container should be labeled with the product name, CAS number, and storage instructions.