(3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid | CAS No. 109744-49-2

(3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid

Basic Information

CAS Number

109744-49-2

Molecular Formula

C12H24O5Si

Molecular Weight

276.41 g/mol

AD

Basic Physical Properties

Boiling Point

327.412°C at 760 mmHg

CC(C)(C)[Si](C)(C)OC(CC(=O)O)CC(=O)OC

InChI

InChI=1S/C12H24O5Si/c1-12(2,3)18(5,6)17-9(7-10(13)14)8-11(15)16-4/h9H,7-8H2,1-6H3,(H,13,14)/t9-/m1/s1

InChIKey

CTZDWHZODOCMCT-SECBINFHSA-N

LogP

2.4146

Topological Polar Surface Area

72.83 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

306

Synonyms & References

English

  • DTXSID50435025
  • (3R)-3-[tert-butyl(dimethyl)silyl]oxy-5-methoxy-5-oxopentanoic acid
  • (3R)-3-(tert-Butyldimethylsilyl)oxypentanedioate-1-methyl monoester
  • (R)-3-((tert-Butyldimethylsilyl)oxy)-5-methoxy-5-oxopentanoic acid
  • AC-770
  • SCHEMBL9802582
  • C12H24O5Si
  • 109744-49-2
  • (3R)-3-{[tert-Butyl(dimethyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid
  • AKOS015892788
  • (R)-3-((tert-Butyldimethylsilyl)oxy)-5-methoxy-5-oxopentanoicacid
  • (3R)-3-[(TERT-BUTYLDIMETHYLSILYL)OXY] PENTANEDIOATE-1-METHYLMONOESTER
  • B-6
  • (3R)-3-[(terbutyldimethylsilyl)oxy]pentanedioate-1-methylmonoester
  • (3R)-3-[(tert-butyldimethylsily)oxy]pentanedioate-1-Methylmonoester
  • (3R)-3-[(t-Butyldimethylsilyl)oxy]pentanedioate-1-methylmonoester,J-4
  • (R)-3-(tert-Butyl-dimethyl-silanyloxy)-pentanedioicacidmonomethylester
  • J-4:(3R)-3-[(tert-butyldimethylsilyl)oxy] pentanedioate-1-methylmonoester
  • Pentanedioic acid, 3-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-, MonoMethyl ester, (R)-

MDL Number

MFCD08458240

Customs Code

2931900090

FAQ

What are the physical and chemical properties of (3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid (CAS: 109744-49-2)?

(3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid is a crystalline compound with a molecular weight of approximately 343.46 g/mol. It has a low solubility in water but is soluble in organic solvents. The compound is reactive, particularly towards nucleophiles and bases. It may undergo hydrolysis under basic conditions.

How is (3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid (CAS: 109744-49-2) typically synthesized?

(3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid is typically synthesized through a multi-step process involving the protection of the carboxylic acid group, followed by the introduction of the silyl ether and methoxy groups. The reaction involves the use of protecting agents and organometallic reagents, and the yield can be improved by optimizing reaction conditions and catalysts.

What industries use (3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid (CAS: 109744-49-2)?

(3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid is utilized in the pharmaceutical industry for the synthesis of certain drug intermediates. It may also find applications in polymer synthesis and as a component in chemical sensors due to its specific functional groups and reactivity.

What precautions should be taken when handling (3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid (CAS: 109744-49-2)?

When handling (3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle the compound in a well-ventilated area or fume hood to avoid inhalation. Spills should be contained and cleaned up with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.

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