Compound Q&A

How is (3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid (CAS: 109744-49-2) typically synthesized?

Answer

(3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid
(3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid is typically synthesized through a multi-step process involving the protection of the carboxylic acid group, followed by the introduction of the silyl ether and methoxy groups. The reaction involves the use of protecting agents and organometallic reagents, and the yield can be improved by optimizing reaction conditions and catalysts.

About

English Name (3R)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-methoxy-5-oxopentanoic acid
Molecular Formula C12H24O5Si
Molecular Weight 276.41 g/mol
SMILES CC(C)(C)[Si](C)(C)OC(CC(=O)O)CC(=O)OC
InChIKey CTZDWHZODOCMCT-SECBINFHSA-N
Last Updated: 2026-01-01 06:12

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