N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-ornithine

Basic Information

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CAS Number

109425-55-0

Molecular Formula

C25H30N2O6

Molecular Weight

454.52 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

127-137°C

Boiling Point

679°C at 760 mmHg

Density

1.2260

Flash Point

364.5 °C

Refractive Index

1.57

Specific Rotation

-7.5° (c=1% in DMF)

SMILES

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CC(C)(C)OC(=O)NCCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

InChI

InChI=1S/C25H30N2O6/c1-25(2,3)33-23(30)26-14-8-13-21(22(28)29)27-24(31)32-15-20-18-11-6-4-9-16(18)17-10-5-7-12-19(17)20/h4-7,9-12,20-21H,8,13-15H2,1-3H3,(H,26,30)(H,27,31)(H,28,29)/t21-/m0/s1

InChIKey

JOOIZTMAHNLNHE-NRFANRHFSA-N

LogP

4.283200000000003

Topological Polar Surface Area

113.96000000000002 Å²

Hydrogen Bond Donor/Acceptor

3 / 8

Complexity

669

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

S-109425-55-0
(S)-5-tert-Butoxycarbonylamino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-pentanoic acid
Nalpha-Fmoc-Ndelta-Boc-L-ornithine
AKOS015924224
(2S)-5-{[(tert-butoxy)carbonyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanoic acid
Fmoc-Orn(Boc)-OH, >=96.0% (HPLC)
CS-W011572
(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-5-(tert-butoxycarbonylamino)pentanoic acid
MFCD00065668
HY-W010856
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((tert-butoxycarbonyl)amino)pentanoic acid
EN300-262356
J-002278
5-t-butoxycarbonylamino-(2S)-(9H-fluoren-9-ylmethoxycarbonylamino)-pentanoic acid
Nalpha-Fmoc-Ndelta-Boc-L-ornithine;Fmoc-Orn(Boc)-OH
I10309
Ndelta-(tert-Butoxycarbonyl)-Nalpha-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine
Fmoc-Orn(Boc)-OH
DTXSID00373246
(2s)-2-(9h-fluoren-9-ylmethoxycarbonylamino)-5-((2-methylpropan-2-yl)oxycarbonylamino)pentanoic acid
B4184
5-t-butoxycarbonylamino-(2S)-(9H-fluoren-9-ylmethoxycarbonyl amino)-pentanoic acid
N5-Boc-N2-Fmoc-L-ornithine
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid
AC-32121
AM10085
JOOIZTMAHNLNHE-NRFANRHFSA-N
Ndelta-Boc-Nalpha-Fmoc-L-ornithine
AS-17433
109425-55-0
N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-delta-t-butyl-oxycarbonyl-L-ornithine

MDL Number

MFCD00065668

Customs Code

2924299090

FAQ

What regulatory guidelines apply to N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-ornithine (CAS: 109425-55-0)?

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonsyl}-L-ornithine (CAS: 109425-55-0) falls under various regulatory guidelines. Under GHS classification, it should be handled as a non-toxic substance. REACH regulations require registration if the substance is manufactured or imported in quantities exceeding one ton per year. FDA and EPA regulations may apply depending on its intended use. Companies should ensure compliance with local chemical regulations and maintain appropriate documentation for safety and environmental protection.

Are there alternatives to N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonsyl}-L-ornithine (CAS: 109425-55-0) in synthesis?

In synthesis, alternatives to N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonsyl}-L-ornithine (CAS: 109425-55-0) include other ornithine derivatives and amino acid analogs. Common alternatives include N-[(9H-Fluoren-9-ylmethoxy)carbonyl]ornithine or other similar fluorenylmethoxycarbonyl (Fmoc) protected amino acids. These alternatives can be chosen based on their availability, cost, and specific reaction requirements.

What is the market or research trend for N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonsyl}-L-ornithine (CAS: 109425-55-0)?

The market and research trend for N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonsyl}-L-ornithine (CAS: 109425-55-0) is focused on its use in peptide synthesis, drug development, and biotechnology applications. There is increasing interest in developing more efficient and safer methods for its synthesis and use in medicinal chemistry. Recent research trends include exploring its potential in targeted drug delivery systems and as a building block for complex peptides.

How should waste containing N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonsyl}-L-ornithine (CAS: 109425-55-0) be handled?

Waste containing N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonsyl}-L-ornithine (CAS: 109425-55-0) should be collected and disposed of according to local regulations. Waste liquids should be neutralized and separated before disposal. Solid waste can be incinerated or disposed of by professional hazardous waste disposal services. Proper handling and storage of waste are crucial to prevent environmental contamination. Companies should ensure compliance with all relevant environmental protection laws.