1,3-Propanedithiol | CAS No. 109-80-8

Q: What is 1,3-Propanedithiol (CAS: 109-80-8)?

1,3-Propanedithiol (CAS: 109-80-8) is a chemical compound with the formula C3H8O2S2. It is a colorless, volatile liquid with a strong sulfur odor, known for its reactivity and use as a functional group in organic synthesis. The compound contains two thiol (-SH) groups attached to the propylene backbone, making it a versatile precursor in pharmaceutical and industrial applications.

Q: What are the main uses of 1,3-Propanedithiol (CAS: 109-80-8)?

1,3-Propanedithiol (CAS: 109-80-8) is widely used in pharmaceuticals for drug synthesis, in polymer science for creating thiol-ene click reactions, and in research for functionalizing molecules. It also serves as an intermediate in the production of pesticides and dyes. Its unique chemical structure enables applications in cross-linking agents and material science, enhancing its industrial relevance.

Q: Is 1,3-Propanedithiol (CAS: 109-80-8) safe?

1,3-Propanedithiol (CAS: 109-80-8) requires careful handling due to its potential to cause skin and eye irritation. It is classified as flammable and may release toxic fumes upon combustion. Safety standards emphasize using personal protective equipment (PPE) like gloves, goggles, and a fume hood. Proper ventilation and adherence to OSHA guidelines are essential to mitigate risks during use.

Q: How should 1,3-Propanedithiol (CAS: 109-80-8) be stored?

1,3-Propanedithiol (CAS: 109-80-8) should be stored in a cool, dry, and well-ventilated area, away from light and heat sources. Keep in tightly sealed, non-reactive containers to prevent moisture absorption. Store in a flammable materials cabinet to ensure stability and safety. Avoid prolonged exposure to air to maintain its chemical integrity.

1,3-Propanedithiol

Basic Information

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CAS Number

109-80-8

Molecular Formula

C3H8S2

Molecular Weight

108.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

-79°C

Boiling Point

170°C

Water Solubility

<0.1 g/100 mL at 21 ºC

Refractive Index

n20/D 1.539(lit.)

Vapor Pressure

5 mmHg ( 37.7 °C)

SMILES

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SCCCS

InChI

InChI=1S/C3H8S2/c4-2-1-3-5/h4-5H,1-3H2

InChIKey

ZJLMKPKYJBQJNH-UHFFFAOYSA-N

LogP

1.2361

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

12.4

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Stability

Stable. Incompatible with oxidizing agents, bases, reducing agents, alkali metals. Store cool.

Synonyms & References

English

1,3-dimercaptopropane
1,3-propanedithiol
dithiotrimethyleneglycol
trimethylene dimercaptan
trimethylenedithioglycol
Propane-1,3-dithiol
1-3-Propanedithiol
Trimethylene Dithiol
PDT
NDR-132
FEMA 3588
1,3-diethyl thiol
1,3-DITHIOPROPANE
1,3-Propandeithiol
Propan-1,3-dithiol
1,3-Propanebisthiol
1,3-Dimercaptopropane
Trimethylene dimercaptan
1,3-Propanedithiol
1,3-PROPANEDITHIOL
propane-1,3-dithiol

MDL Number

MFCD00004904

Customs Code

29309070

FAQ

What is 1,3-Propanedithiol (CAS: 109-80-8)?

1,3-Propanedithiol (CAS: 109-80-8) is a chemical compound with the formula C3H8O2S2. It is a colorless, volatile liquid with a strong sulfur odor, known for its reactivity and use as a functional group in organic synthesis. The compound contains two thiol (-SH) groups attached to the propylene backbone, making it a versatile precursor in pharmaceutical and industrial applications.

What are the main uses of 1,3-Propanedithiol (CAS: 109-80-8)?

1,3-Propanedithiol (CAS: 109-80-8) is widely used in pharmaceuticals for drug synthesis, in polymer science for creating thiol-ene click reactions, and in research for functionalizing molecules. It also serves as an intermediate in the production of pesticides and dyes. Its unique chemical structure enables applications in cross-linking agents and material science, enhancing its industrial relevance.

Is 1,3-Propanedithiol (CAS: 109-80-8) safe?

1,3-Propanedithiol (CAS: 109-80-8) requires careful handling due to its potential to cause skin and eye irritation. It is classified as flammable and may release toxic fumes upon combustion. Safety standards emphasize using personal protective equipment (PPE) like gloves, goggles, and a fume hood. Proper ventilation and adherence to OSHA guidelines are essential to mitigate risks during use.

How should 1,3-Propanedithiol (CAS: 109-80-8) be stored?

1,3-Propanedithiol (CAS: 109-80-8) should be stored in a cool, dry, and well-ventilated area, away from light and heat sources. Keep in tightly sealed, non-reactive containers to prevent moisture absorption. Store in a flammable materials cabinet to ensure stability and safety. Avoid prolonged exposure to air to maintain its chemical integrity.