9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride (1:1)

Basic Information

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CAS Number

108929-04-0

Molecular Formula

C16H16ClN3

Molecular Weight

285.78 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

275°C(dec.)

Boiling Point

428ºC at 760 mmHg

Density

1.32g/cm3

Flash Point

212.7ºC

Solubility

H2O: soluble38mg/mL

SMILES

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C1C2C3=CC=CC=C3CC4=CC=CC=C4N2C(=N1)N.Cl

InChI

InChI=1S/C16H15N3.ClH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H

InChIKey

VKXSGUIOOQPGAF-UHFFFAOYSA-N

LogP

2.888600000000001

Topological Polar Surface Area

41.62 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

378

Safety Information

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Toxicity

LD50 in male, female rats (mg/kg): 314, 192 orally; 17, 22 i.v. (Nishikawa)

Synonyms & References

English

Epinastine hydrochloride [JAN]
1H-Dibenz[c,f]imidazo[1,5-a]azepin-3-amine, 9,13b-dihydro-,hydrochloride
EPINASTINE HYDROCHLORIDE (MART.)
WAL-801CL HCl
IH-Dibenz(c,f)imidazo(1,5-a)azepin-3-amine, 9,13b-dihydro-, monohydrochloride
3-Amino-9,13b-dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepine monohydrochloride
F17420
Epinastine hydrochloride
EX-A1004
AC-1491
Epinastine hydrochloride, >=98% (HPLC), solid
Epinastinehydrochloride
KS-1159
EPINASTINE HYDROCHLORIDE (USP-RS)
(13bRS)-9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride; 1H-Dibenz[c,f]imidazo[1,5-a]azepin-3-amine, 9,13b-dihydro-, monohydrochloride (9CI); Alesion; Elestat; Epinastine hydrochloride; WAL 801CL
Q27122286
Elestat
Tox21_112263
CAS-108929-04-0
Elestat (TN)
VKXSGUIOOQPGAF-UHFFFAOYSA-N
BCP12119
EPINASTINE HYDROCHLORIDE [USP-RS]
D01713
WAL-802-CL
SCHEMBL122749
108929-04-0
9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride
Flurinol
CS-0013220
2,4-diazatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),3,7,9,11,14,16-heptaen-3-amine;hydrochloride

MDL Number

MFCD00933434

Customs Code

2933990090

FAQ

What regulatory guidelines apply to 9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride (CAS: 108929-04-0)?

9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride (CAS: 108929-04-0) is subject to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), requiring proper handling, storage, and disposal. In the European Union, it is regulated under REACH for potential health and environmental risks. FDA and EPA guidelines also apply for its use in pharmaceuticals and environmental releases, respectively.

Are there alternatives to 9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride (CAS: 108929-04-0) in synthesis?

There are alternative reagents and compounds that can be used in place of 9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride (CAS: 108929-04-0) depending on the specific application. For instance, other azepin-3-amine derivatives or similar dihydrobenzimidazoles can serve as viable alternatives in various synthetic pathways.

What is the market or research trend for 9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride (CAS: 108929-04-0)?

The market for 9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride (CAS: 108929-04-0) is growing due to its potential applications in pharmaceuticals and as a research compound. Research trends are focusing on its biological activity and potential therapeutic uses, particularly in neurology and oncology. Market demand is likely to increase with further validation of its efficacy and safety.

How should waste containing 9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride (CAS: 108929-04-0) be handled?

Waste containing 9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride (CAS: 108929-04-0) should be collected in appropriate containers and stored away from heat and ignition sources. The waste should be handled in accordance with local regulations, and it may require neutralization or biodegradation before disposal. Incineration or professional waste disposal services are recommended to ensure environmental safety and compliance with legal requirements.