3,5-Dibromo-2-Chloropyrazine

Basic Information

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CAS Number

1082843-70-6

Molecular Formula

C4HBr2ClN2

Molecular Weight

272.33 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

261 ºC

Flash Point

112 ºC

SMILES

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C1=C(N=C(C(=N1)Cl)Br)Br

InChI

InChI=1S/C4HBr2ClN2/c5-2-1-8-4(7)3(6)9-2/h1H

InChIKey

WNZURIDUDWMEKQ-UHFFFAOYSA-N

LogP

2.6550000000000002

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

103

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

3,5-Dibromo-2-chloropyrazine
2-Chloro-3,5-dibromopyrazine
3,5-dibromo-2-chloropyrazine
GS-5765
DB-059726
A895296
W-204664
WNZURIDUDWMEKQ-UHFFFAOYSA-N
1082843-70-6
2-chloro-3,5-dibromo-pyrazine
3,5-dibromo-2-chloro-pyrazine
PB28518
J-511250
CS-W000798
C4HBr2ClN2
SY019258
AMY28628
DTXSID90693607
SCHEMBL279689
MFCD13193367
AKOS015919885
3,5-Dibromo-2-Chloropyrazine

MDL Number

MFCD13193367

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 3,5-Dibromo-2-Chloropyrazine (CAS: 1082843-70-6)?

3,5-Dibromo-2-Chloropyrazine (CAS: 1082843-70-6) is a crystalline solid with a molecular weight of approximately 286.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. This compound exhibits moderate reactivity, particularly towards nucleophiles and reducing agents. It is stable under normal conditions but should be stored in a cool, dry place away from moisture and heat.

How is 3,5-Dibromo-2-Chloropyrazine (CAS: 1082843-70-6) typically synthesized?

3,5-Dibromo-2-Chloropyrazine (CAS: 1082843-70-6) is typically synthesized through the reaction of 2-chloropyrazine with bromine in the presence of a catalyst such as iron(III) chloride. The reaction yields a mixture of isomers, and the desired product can be isolated by recrystallization. The yield is generally around 70-80%, and the reaction is exothermic, requiring careful temperature control.

What industries use 3,5-Dibromo-2-Chloropyrazine (CAS: 1082843-70-6)?

3,5-Dibromo-2-Chloropyrazine (CAS: 1082843-70-6) is used in various industries, particularly in the pharmaceutical sector for the synthesis of certain drug intermediates. It is also employed in the polymer industry for the production of speciality polymers, and in the chemical sensing field for developing gas sensors. Additionally, it has applications in the semiconductor industry as a dopant material.

What precautions should be taken when handling 3,5-Dibromo-2-Chloropyrazine (CAS: 1082843-70-6)?

When handling 3,5-Dibromo-2-Chloropyrazine (CAS: 1082843-70-6), appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. It should be handled in a fume hood to prevent inhalation of vapors. Spills should be carefully cleaned up using appropriate absorbents, and the area should be well-ventilated. In case of skin contact or inhalation, seek medical attention immediately. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.