2,4,6-Trimethylpyridine

Basic Information

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CAS Number

108-75-8

Molecular Formula

C8H11N

Molecular Weight

121.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

−43 °C

Boiling Point

171-172 °C

Water Solubility

35 g/L (20 ºC)

Solubility

35g/l

Refractive Index

n20/D 1.498(lit.)

SMILES

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Cc1cc(C)nc(C)c1

InChI

InChI=1S/C8H11N/c1-6-4-7(2)9-8(3)5-6/h4-5H,1-3H3

InChIKey

BWZVCCNYKMEVEX-UHFFFAOYSA-N

LogP

2.00686

pKa

7.43(at 25℃)

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

80.6

Safety Information

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GHS Hazard Pictograms

H226

H302

H311

H315

H319

H332

H335

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H302 Harmful if swallowed
Acute toxicity, oral

H311 Toxic in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 3 Class 3

Stability

Stable. Combustible. Incompatible with strong oxidizing agents.

Sensitiveness

Hygroscopic

Synonyms & References

English

2,4,6-Trimethylpyridine
sym.-collidine
2,4,6-Collidine
2,4,6-Collidineneat
s-Collidine
246CO
g-Collidine
SYM COLLIDINE
2,4,6-Kollidin
GAMMA-COLLIDINE
a,g,a'-Collidine
#nsym.-Collidine
2,4,6-Collidine99%
TMP
S-COLLIDINE
2,4,6-COLLIDINE
2,4,6-trimethylpyridine

MDL Number

MFCD00006338

Customs Code

2933399010

FAQ

What is 2,4,6-Trimethylpyridine (CAS: 108-75-8)?

2,4,6-Trimethylpyridine (CAS: 108-75-8) is an organic compound with the chemical formula C9H12N. It is a derivative of pyridine, featuring methyl groups attached to the 2, 4, and 6 positions. This compound is known for its aromatic properties and is commonly used in various chemical applications. It appears as a colorless liquid with a mild odor and is slightly soluble in water.

What are the main uses of 2,4,6-Trimethylpyridine (CAS: 108-75-8)?

2,4,6-Trimethylpyridine (CAS: 108-75-8) is widely used in the synthesis of pharmaceuticals, such as antifungal and antibiotic agents. It also serves as an intermediate in the production of dyes, pesticides, and other industrial chemicals. Additionally, it finds applications in research for organic synthesis and as a solvent in some chemical processes. Its versatility makes it relevant in both industrial and academic settings.

Is 2,4,6-Trimethylpyridine (CAS: 108-75-8) safe?

2,4,6-Trimethylpyridine (CAS: 108-75-8) is generally considered safe when handled properly. However, it may cause skin and eye irritation, and inhalation can lead to respiratory issues. Safety standards recommend using personal protective equipment, such as gloves and goggles, during handling. It is also important to follow proper ventilation and storage guidelines to minimize exposure and ensure safe use.

How should 2,4,6-Trimethylpyridine (CAS: 108-75-8) be stored?

2,4,6-Trimethylpyridine (CAS: 108-75-8) should be stored in a cool, dry, and well-ventilated area, away from direct sunlight. It is best kept in a sealed container made of materials resistant to chemical reactions, such as glass or stainless steel. Maintaining a storage temperature below 25°C and avoiding high humidity levels ensures its stability and prolongs shelf life. Proper labeling and storage conditions are crucial for safety and compliance.