1-Bromo-3-chlorobenzene

Basic Information

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CAS Number

108-37-2

Molecular Formula

C6H4BrCl

Molecular Weight

191.45 g/mol

Chemical Classification

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

-21.5 ºC

Boiling Point

196°C

Refractive Index

n20/D 1.576(lit.)

SMILES

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C1=CC(=CC(=C1)Br)Cl

InChI

InChI=1S/C6H4BrCl/c7-5-2-1-3-6(8)4-5/h1-4H

InChIKey

JRGGUPZKKTVKOV-UHFFFAOYSA-N

LogP

3.102500000000001

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

74.9

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

1-bromo-3-chlorobenzene;m-Chlorobromobenzene
FT-0615217
EN300-57106
m-Chlorophenyl bromide
MFCD00000568
W-108721
EINECS 203-575-8
1-bromo-3-chloro-benzene
InChI=1/C6H4BrCl/c7-5-2-1-3-6(8)4-5/h1-4
NS00023499
Bromochlorobenzene, m-
108-37-2
1-Chloro-3-bromobenzene
3-BROMOPHENYL CHLORIDE
3-Chlorobromobenzene
NSC 53548
Benzene, 1-bromo-3-chloro-
Q27251451
AKOS005265595
1-Bromo-3-chlorobenzene
A801865
CS-W010720
3-bromo-1-chlorobenzene
12Y161X15C
3-chloro-1-bromobenzene
STR03612
NSC-53548
DL-CAMPHORICANHYDRIDE
SY001585
SCHEMBL264446
1 -bromo-3-chlorobenzene

MDL Number

MFCD00000568

Customs Code

2903999090

FAQ

What is 1-Bromo-3-chlorobenzene (CAS: 108-37-2)?

1-Bromo-3-chlorobenzene (CAS: 108-37-2) is a brominated and chlorinated aromatic compound with the chemical formula C6H4ClBr. It is a colorless liquid with a characteristic aromatic odor, known for its stability and reactivity in organic synthesis. The molecule features bromo and chloro substituents on adjacent carbon atoms of a benzene ring, making it a key intermediate in various chemical applications.

What are the main uses of 1-Bromo-3-chlorobenzene (CAS: 108-37-2)?

1-Bromo-3-chlorobenzene (CAS: 108-37-2) is widely used in pharmaceuticals as a building block for drug synthesis, in industry for producing dyes and agrochemicals, and in research as a versatile organic intermediate. Its unique halogen substituents enable functional group manipulation, supporting applications in chemical manufacturing and material science.

Is 1-Bromo-3-chlorobenzene (CAS: 108-37-2) safe?

1-Bromo-3-chlorobenzene (CAS: 108-37-2) requires careful handling due to its potential toxicity. It may cause skin and eye irritation, and inhalation should be avoided. Safety measures include wearing protective gloves, goggles, and a lab coat, and working in a well-ventilated area. Always follow OSHA and EPA guidelines when handling this hazardous chemical.

How should 1-Bromo-3-chlorobenzene (CAS: 108-37-2) be stored?

1-Bromo-3-chlorobenzene (CAS: 108-37-2) should be stored in a sealed, cool, and dry container, away from light and incompatible materials. Maintain storage temperature below 25°C and ensure low humidity to prevent degradation. Use airtight containers made of glass or inert plastic, and store in a ventilated area to avoid vapor accumulation.