7-Quinolinecarboxylic acid

Basic Information

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CAS Number

1078-30-4

Molecular Formula

C10H7NO2

Molecular Weight

173.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

249.5°C

Boiling Point

348.7°C at 760 mmHg

Refractive Index

1.5200 (estimate)

SMILES

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C1=CC2=C(C=C(C=C2)C(=O)O)N=C1

InChI

InChI=1S/C10H7NO2/c12-10(13)8-4-3-7-2-1-5-11-9(7)6-8/h1-6H,(H,12,13)

InChIKey

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LogP

1.9329999999999998

Topological Polar Surface Area

50.19 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

205

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

DTXSID50344784
BCP10039
SY065640
7-Quinolinecarboxylicacid
FS-2897
F2191-0006
AC-4532
PS-8648
FT-0633308
AKOS000270294
EN300-97215
7-quinoline carboxylic acid
Quinoline-7-carboxylic acid
SCHEMBL1145034
7-Quinolinecarboxylic acid
MFCD00047617
MB00424
W-204648
7-Carboxyquinoline
1078-30-4
AM802903
A801765
Z1198148848
CS-D0464
quinolin-7-carboxylic acid
7-Carboxyquinoline, 7-Carboxy-1-azanaphthalene
AKOS BBS-00005341
7-QUINOLINEcarboxylic acid 98%
7-Quinolinecarboxylic acid ,98%
7-Quinolinecarboxylic acid, 95+%
WXXVQWSDMOAHHV-UHFFFAOYSA-N

MDL Number

MFCD00047617

Customs Code

2933499090

FAQ

What are the physical and chemical properties of 7-Quinolinecarboxylic acid (CAS: 1078-30-4)?

7-Quinolinecarboxylic acid is a crystalline solid with a molecular weight of approximately 169.14 g/mol. It has a solubility of about 0.2 g/100 mL in water. Chemically, it is mildly acidic and can react with bases to form salts. It is also reactive towards nucleophiles, demonstrating good reactivity in aromatic substitution reactions.

How is 7-Quinolinecarboxylic acid (CAS: 1078-30-4) typically synthesized?

7-Quinolinecarboxylic acid is commonly synthesized by the condensation of 2-chloroquinoline with an acid catalyst, such as p-toluenesulfonic acid. The reaction yields a mixture that can be purified by recrystallization or column chromatography.

What industries use 7-Quinolinecarboxylic acid (CAS: 1078-30-4)?

7-Quinolinecarboxylic acid finds applications in the pharmaceutical industry for drug synthesis, in the polymer industry for functional polymer modification, and in the sensor technology for chemical sensing due to its acidic and functional groups.

What precautions should be taken when handling 7-Quinolinecarboxylic acid (CAS: 1078-30-4)?

When handling 7-Quinolinecarboxylic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of a spill, the area should be ventilated and the spill cleaned up using appropriate chemical spill kits. Always refer to the Safety Data Sheet (SDS) for detailed safety information.