7-Quinolinecarboxylic acid(CAS: 1078-30-4)

7-Quinolinecarboxylic acid is a crystalline solid with a molecular weight of approximately 169.14 g/mol. It has a solubility of about 0.2 g/100 mL in water. Chemically, it is mildly acidic and can react with bases to form salts. It is also reactive towards nucleophiles, demonstrating good reactivity in aromatic substitution reactions.

7-Quinolinecarboxylic acid is commonly synthesized by the condensation of 2-chloroquinoline with an acid catalyst, such as p-toluenesulfonic acid. The reaction yields a mixture that can be purified by recrystallization or column chromatography.

7-Quinolinecarboxylic acid finds applications in the pharmaceutical industry for drug synthesis, in the polymer industry for functional polymer modification, and in the sensor technology for chemical sensing due to its acidic and functional groups.

When handling 7-Quinolinecarboxylic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of a spill, the area should be ventilated and the spill cleaned up using appropriate chemical spill kits. Always refer to the Safety Data Sheet (SDS) for detailed safety information.