Amyloid β Protein Fragment 1-42

Basic Information

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CAS Number

107761-42-2

Molecular Formula

C203H311N55O60S1

Molecular Weight

4514.04 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

SMILES

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NCCCCCC(NCC(NCC(NCC(NCC(NCC(NCC(NCC(NCC(NCC(NCC(NCC(NCC(NCC(NCC(NCC(NCC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

InChI

InChI=1S/C38H62N18O17/c39-5-3-1-2-4-23(58)42-7-25(60)44-9-27(62)46-11-29(64)48-13-31(66)50-15-33(68)52-17-35(70)54-19-37(72)56-21-38(73)55-20-36(71)53-18-34(69)51-16-32(67)49-14-30(65)47-12-28(63)45-10-26(61)43-8-24(59)41-6-22(40)57/h1-21,39H2,(H2,40,57)(H,41,59)(H,42,58)(H,43,61)(H,44,60)(H,45,63)(H,46,62)(H,47,65)(H,48,64)(H,49,67)(H,50,66)(H,51,69)(H,52,68)(H,53,71)(H,54,70)(H,55,73)(H,56,72)

InChIKey

XPESWQNHKICWDY-QYFPAAMGSA-N

LogP

1.35150

Topological Polar Surface Area

534.71 Å²

Hydrogen Bond Donor/Acceptor

20 / 35

Complexity

11400

Synonyms & References

English

Bate-Amyloid（1-42）human
(1-42) (human)
AB42, betaamyloid peptide
Amyloid βH-Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
REF DUPL: H-Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
Beta-Amyloid (1-42), sodium salt
Β-AMYLOID PEPTIDE (1-42), RAT
beta-Amyloid (1-42) human
L-alpha-Aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-serylglycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-L-methionyl-L-valylglycylglycyl-L-valyl-L-valyl-L-isoleucyl-L-alanine
Amyloid β Protein Fragment 1-42
Amyloid β-Protein (1-42)
Amyloid beta-Protein (Human, 1-42)
Amyloid β-Peptide (1-42) (human)
Amyloid β-Protein (1-42) (HFIP-treated)
BETA-AMYLOID PEPTIDE(1-42)
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
TB500
β-Amyloid Peptide (1-42), rat
Amyloid Beta-Peptide (1-42) (human)
Amyloid?
A-Peptide (1-42) (human)
Bate-Amyloid(1-42)
2-Amyloid(1-42) Human
(1-42) (human)
Beta-AMyloid(1-42)TB500
AMyloid b-Protein (1-42)
AMyloid (1-42) huMan peptide
Amyloidb-Peptide(1-42)(human)
β-Amyloid (1-42), human TFA
Amyloid β Protein Fragment 1-42， TFA

MDL Number

MFCD00163049

Customs Code

29332900

FAQ

What is Amyloid β Protein Fragment 1-42 (CAS: 107761-42-2)?

Amyloid β Protein Fragment 1-42 (CAS: 107761-42-2) is a peptide fragment derived from the amyloid β protein, which is implicated in the pathogenesis of Alzheimer's disease. It is commonly used in research to study neurodegenerative processes and is known for its ability to form fibrils. The fragment has a molecular weight of approximately 4,238 Da and is typically synthesized for laboratory use.

What are the main uses of Amyloid β Protein Fragment 1-42 (CAS: 107761-42-2)?

Amyloid β Protein Fragment 1-42 (CAS: 107761-42-2) is primarily used in research related to Alzheimer's disease and other neurodegenerative disorders. It is also employed in the development of diagnostic tools and therapeutic agents targeting amyloid accumulation. Additionally, it serves as a model compound for studying protein misfolding and aggregation in biological systems.

Is Amyloid β Protein Fragment 1-42 (CAS: 107761-42-2) safe?

Amyloid β Protein Fragment 1-42 (CAS: 107761-42-2) is generally considered safe when handled properly in controlled laboratory settings. However, due to its potential to form toxic aggregates, it requires careful handling to minimize exposure. Safety protocols include wearing protective gloves and goggles, and working in a fume hood. It is not approved for human or animal use and should be treated as a research chemical.

How should Amyloid β Protein Fragment 1-42 (CAS: 107761-42-2) be stored?

Amyloid β Protein Fragment 1-42 (CAS: 107761-42-2) should be stored at 4°C in a dry, dark place to maintain stability and prevent degradation. It is recommended to keep it in airtight containers to avoid moisture exposure. For long-term storage, it can be frozen at -20°C. Always ensure proper labeling and store away from incompatible substances.