[2-(Benzyloxy)-3-pyridinyl]boronic acid

Basic Information

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CAS Number

1072952-41-0

Molecular Formula

C12H12BNO3

Molecular Weight

229.04 g/mol

Basic Physical Properties

Melting Point

145-147°C

SMILES

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OB(c1cccnc1OCc1ccccc1)O

InChI

InChI=1S/C12H12BNO3/c15-13(16)11-7-4-8-14-12(11)17-9-10-5-2-1-3-6-10/h1-8,15-16H,9H2

InChIKey

YTIGWZQYGHOXOB-UHFFFAOYSA-N

LogP

0.3404

Topological Polar Surface Area

62.58000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Synonyms & References

English

(2-(Benzyloxy)pyridin-3-yl)boronic acid
2-Benzyloxypyridin-3-ylboronic acid
(2-Benzyloxy-3-pyridyl)boronic acid
2-(Benzyloxy)pyridine-3-boronic acid
2-Benzyloxypyridine-3-boronic acid
2-Benzyloxypyridine-3-boronic-acid
Boronic acid, B-[2-(phenylmethoxy)-3-pyridinyl]-
(2-phenylmethoxypyridin-3-yl)boronic acid
(2-(benzyloxy)pyridin-3-yl)boronic acid

MDL Number

MFCD06798264

FAQ

What is [2-(Benzyloxy)-3-pyridinyl]boronic acid (CAS: 1072952-41-0)?

[2-(Benzyloxy)-3-pyridinyl]boronic acid (CAS: 1072952-41-0) is an organoboron compound with the molecular formula C12H10BN2O2. It is a white crystalline solid with a pyridine ring substituted with a benzyloxy group and a boron atom. This compound is often used in organic synthesis and as a ligand in various chemical reactions.

What are the main uses of [2-(Benzyloxy)-3-pyridinyl]boronic acid (CAS: 1072952-41-0)?

[2-(Benzyloxy)-3-pyridinyl]boronic acid (CAS: 1072952-41-0) is primarily used in organic synthesis as a reagent. It serves as a boronic acid derivative and is particularly useful in Suzuki couplings and other cross-coupling reactions. Additionally, it finds applications in the preparation of pharmaceuticals and as a protective group in chemical research.

Is [2-(Benzyloxy)-3-pyridinyl]boronic acid (CAS: 1072952-41-0) safe?

[2-(Benzyloxy)-3-pyridinyl]boronic acid (CAS: 1072952-41-0) is generally considered safe when handled with proper precautions. However, it should be stored in a cool, dry place away from direct sunlight and heat. Protective gloves and goggles should be worn during handling due to its potential to irritate the skin and eyes. Ensure good ventilation in the work area.

How should [2-(Benzyloxy)-3-pyridinyl]boronic acid (CAS: 1072952-41-0) be stored?

[2-(Benzyloxy)-3-pyridinyl]boronic acid (CAS: 1072952-41-0) should be stored at room temperature in a cool, dry environment, protected from direct sunlight. It should be kept in a tightly sealed container to prevent moisture absorption. Avoid storing it near heat sources, as it can degrade under high temperatures. Store it away from incompatible materials such as acids and strong oxidizers.