5-Chloro-2-pyridinamine

Basic Information

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CAS Number

1072-98-6

Molecular Formula

C5H5ClN2

Molecular Weight

128.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

135-138 °C

Boiling Point

127-128 °C/11 mmHg

Water Solubility

1 g/L (20 ºC)

Solubility

1.0g/l

Refractive Index

1.5110 (estimate)

Vapor Pressure

0.0±0.5 mmHg at 25°C

SMILES

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C1=CC(=NC=C1Cl)N

InChI

InChI=1S/C5H5ClN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)

InChIKey

MAXBVGJEFDMHNV-UHFFFAOYSA-N

LogP

1.3172

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

76.8

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Sensitive to light and air

Synonyms & References

English

J8TAP6NFD4
EN300-19819
2-amino-5-chloropyridin
F0001-0149
5-Chloro-2-aminopyridine
5-chloropyridine-2-amine
AC-2429
2-amino5-chloropyridine
AI3-52448
5-Chloro-2-pyridinamine;5-Chloropyridin-2-amine
2-Amino-5-chloropyridine, 98%
2-amino-5-cloropyridine
AG-617/02036012
CS-W018533
NSC26283
Q-103358
5-chloropyridin-2-ylamine
RP-26695
2-amino-5-chloro pyridine
2-Amino-5-chloropyridine, purum, >=98.0% (NT)
MFCD00006324
PS-3640
BCP23345
A0837
2-Amino-5-chloropyridine, British Pharmacopoeia (BP) Reference Standard
2-Amino-5-Chloro-pyridine
EINECS 214-020-4
AKOS000119653
2-Pyridinamine, 5-chloro-
SCHEMBL77304
CCG-325545

MDL Number

MFCD00006324

Customs Code

2942000000

FAQ

What is 5-Chloro-2-pyridinamine (CAS: 1072-98-6)?

5-Chloro-2-pyridinamine, with the CAS number 1072-98-6, is a chemical compound containing a pyridine ring substituted with a chlorine atom at the 5-position and an amino group at the 2-position. It is a white to off-white crystalline solid with a molecular formula of C5H5ClN2 and a molecular weight of 129.58 g/mol. This compound is known for its stability under normal conditions and is commonly used in organic synthesis and pharmaceutical research.

What are the main uses of 5-Chloro-2-pyridinamine (CAS: 1072-98-6)?

5-Chloro-2-pyridinamine (CAS: 1072-98-6) is primarily used in the pharmaceutical industry for the synthesis of various drugs and medicinal compounds. It serves as an intermediate in the production of anticonvulsants, antibiotics, and other therapeutic agents. Additionally, it finds applications in chemical research, dye manufacturing, and as a building block for more complex organic molecules.

Is 5-Chloro-2-pyridinamine (CAS: 1072-98-6) safe?

5-Chloro-2-pyridinamine (CAS: 1072-98-6) is generally considered safe when handled properly. However, it may cause skin and eye irritation, and inhalation could be harmful. Safety data sheets recommend using appropriate protective equipment, such as gloves and goggles, and working in a well-ventilated area. It should be stored away from incompatible substances and in compliance with standard chemical safety regulations.

How should 5-Chloro-2-pyridinamine (CAS: 1072-98-6) be stored?

5-Chloro-2-pyridinamine (CAS: 1072-98-6) should be stored in a cool, dry, and dark place, preferably at temperatures below 25°C. It is sensitive to moisture and light, so it should be kept in a sealed container and away from direct sunlight. Proper storage ensures its stability and prevents degradation, which is crucial for maintaining its chemical integrity and effectiveness in pharmaceutical and research applications.