Sodium 1,1,1,3,3,3-hexamethyldisilazan-2-ide

Basic Information

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CAS Number

1070-89-9

Molecular Formula

C6H18NNaSi2

Molecular Weight

183.37 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

171-175 °C

Boiling Point

67°C

Solubility

Soluble in hexane, toluene, ether,terahydrofuran, benzene and toluene.

SMILES

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C[Si](C)(C)[N-][Si](C)(C)C.[Na+]

InChI

InChI=1S/C6H18NSi2.Na/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1

InChIKey

WRIKHQLVHPKCJU-UHFFFAOYSA-N

LogP

2.42250

Complexity

80.9

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 4.3 Class 4.3

Sensitiveness

Moisture Sensitive

Synonyms & References

English

sodium bistrimethylsilyl amide
n-sodium hexamethyldisilazane
sodium bis-(trimethylsilyl) amide
sodium bis-trimethylsilyl amide
sodium bis (trimethylsilyl) amide
sodium bis(trimethylsilyl)-amide
sodium bis trimethylsilylamide
sodium-bis(trimethylsilyl)amide
sodium 1,1,1,3,3,3-hexamethyldisilazan-2-ide
sodium hexamethyidisilazide
sodium bis(trimethyl-silyl)amide
NS00079519
Silanamine, 1,1,1-trimethyl-N-(trimethylsilyl)-, sodium salt
Q2742490
Sodium bis trimethylsilyl amide
sodium bis(trimethyl-silyl)-amide
Hexamethyldisilazane sodium salt
DTXSID5061451
sodium 1,1,1,3,3,3-hexamethyldisilazan-2-id
Sodium bis(trimethylsily)amide
sodium;bis(trimethylsilyl)azanide
sodium bistrimethylsilylamide
Sodium bis(trimethylsilyl)amide 2M in THF
Sodium bis(trimethylsilyl)amide, 2M in THF
Sodium bis (trimethylsilyl) amide 1M in THF
Silanamine, 1,1,1-trimethyl-N-(trimethylsilyl)-, sodium salt (1:1)
NaHMDS
S14981
NaN(TMS)2
1070-89-9
sodium hexamethyldisilazid

MDL Number

MFCD00009835

Customs Code

2931900090

FAQ

What is Sodium 1,1,1,3,3,3-hexamethyldisilazan-2-ide (CAS: 1070-89-9)?

Sodium 1,1,1,3,3,3-hexamethyldisilazan-2-ide (CAS: 1070-89-9) is an organosilicon compound commonly used as a reagent in chemical synthesis. It has the chemical formula C6H18Na2Si2 and is characterized by its stability and reactivity in organic reactions. The compound is often employed in the deprotection of silicon-based protecting groups due to its ability to cleave siloxane bonds under appropriate conditions.

What are the main uses of Sodium 1,1,1,3,3,3-hexamethyldisilazan-2-ide (CAS: 1070-89-9)?

Sodium 1,1,1,3,3,3-hexamethyldisilazan-2-ide (CAS: 1070-89-9) is primarily used in pharmaceutical research for the synthesis of complex organic molecules. It also finds applications in the chemical industry for silane activation and in materials science for surface modification. In research settings, it is valuable for functional group manipulation and as a precursor in the development of new chemical compounds.

Is Sodium 1,1,1,3,3,3-hexamethyldisilazan-2-ide (CAS: 1070-89-9) safe?

Sodium 1,1,1,3,3,3-hexamethyldisilazan-2-ide (CAS: 1070-89-9) is generally considered safe when handled properly. However, it may cause skin and eye irritation upon contact, and inhalation can lead to respiratory issues. Safety measures include wearing appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It is important to follow standard chemical safety protocols to ensure safe handling and storage.

How should Sodium 1,1,1,3,3,3-hexamethyldisilazan-2-ide (CAS: 1070-89-9) be stored?

Sodium 1,1,1,3,3,3-hexamethyldisilazan-2-ide (CAS: 1070-89-9) should be stored in a cool, dry, and well-ventilated area away from moisture and incompatible substances. It is typically kept in a sealed container in a refrigerator at 2–8°C to maintain stability. Avoid exposure to light and ensure proper labeling to prevent accidental contamination or misuse.