Albendazole EP Impurity E (Fenbendazole EP Impurity A, Fenbendazole USP Related Compound A, Carbendazim) | CAS No. 10605-21-7

Q: What is Albendazole EP Impurity E (CAS: 10605-21-7)?

Albendazole EP Impurity E, also known as Fenbendazole EP Impurity A, Fenbendazole USP Related Compound A, and Carbendazim, is a chemical compound with the CAS number 10605-21-7. It is a benzimidazole derivative, commonly used as an impurity in the production of albendazole and fenbendazole. This compound is characterized by its white to off-white crystalline appearance and has a molecular formula of C13H14N2O2S.

Q: What are the main uses of Albendazole EP Impurity E (CAS: 10605-21-7)?

Albendazole EP Impurity E is primarily used in pharmaceutical quality control to identify and quantify impurities in albendazole and fenbendazole drugs. It may also be relevant in research settings for studying related compounds and their effects. Additionally, it is used in the chemical industry for the synthesis of other benzimidazole-based compounds and in food safety testing for trace analysis of veterinary drug residues.

Q: Is Albendazole EP Impurity E (CAS: 10605-21-7) safe?

Albendazole EP Impurity E is generally considered safe when handled properly, but it should be treated with caution due to its potential toxicity. It is important to follow safety guidelines, use appropriate personal protective equipment (PPE), and ensure proper ventilation during handling. Regulatory standards emphasize the need for controlled exposure and safe disposal to minimize health and environmental risks.

Q: How should Albendazole EP Impurity E (CAS: 10605-21-7) be stored?

Albendazole EP Impurity E should be stored in a cool, dry, and dark place, away from sources of heat and moisture. It is recommended to keep it in a sealed container at a temperature below 25°C and maintain low humidity levels. Avoid exposure to direct sunlight and ensure proper ventilation to preserve its stability and purity over time.

Albendazole EP Impurity E (Fenbendazole EP Impurity A, Fenbendazole USP Related Compound A, Carbendazim)

Basic Information

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CAS Number

10605-21-7

Molecular Formula

C9H9N3O2

Molecular Weight

191.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

>300 °C

Boiling Point

326.92°C (rough estimate)

Water Solubility

<0.1 g/100 mL at 21 ºC

Flash Point

11 °C

Solubility

pyridine: soluble1%, clear, very faintly brownish-yellow

Refractive Index

1.6500 (estimate)

SMILES

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COC(=O)Nc1nc2ccccc2[nH]1

InChI

InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)

InChIKey

TWFZGCMQGLPBSX-UHFFFAOYSA-N

LogP

1.7411999999999996

pKa

4.48(at 25℃)

Topological Polar Surface Area

67.00999999999999 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

222

Safety Information

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GHS Hazard Pictograms

H340

H360

H410

Hazard Statement

H340 May cause genetic defects
Germ cell mutagenicity

H360 May damage fertility or the unborn child
Reproductive toxicity

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Synonyms & References

English

1H-Benzimidazole-2-carbamic acid methyl ester
methyl benzimidazol-2-ylcarbamate
Methyl-1H-benzimidazol-2-yl carbamate
Carbendazol
Bavistin
Derosal
Delsene
Methyl 2-benzimidazolecarbamate
2-Benzimidazolecarbamic acid methyl ester
2-(Carbomethoxyamino)benzimidazole
BCM
N-(benzimidazlyl-2)methyl carbamate(effective constituent)
Carbendazim
Carbendazim Solution
Methomyl Technical
1H-BenziMidazol-2-ylcarbaMic acid Methyl ester
2-(MethoxycarbonylaMino)benziMidazole
BCM,Carbendazim,Methyl 2-benzimidazolecarbamate
BCM,Methyl 2-benzimidazolecarbamate,Methyl benzimidazol-2-ylcarbamate
bmk
Fenbendazole impurity A
MBCA
methyl 1H-1,3-benzimidazol-2-ylcarbamate
methyl N-1H-benzimidazol-2-ylcarbamate
Methyl-2-ben
myco
spin
stein
MBC
a118
g665

MDL Number

MFCD00055390

Customs Code

2933990013

FAQ

What is Albendazole EP Impurity E (CAS: 10605-21-7)?

Albendazole EP Impurity E, also known as Fenbendazole EP Impurity A, Fenbendazole USP Related Compound A, and Carbendazim, is a chemical compound with the CAS number 10605-21-7. It is a benzimidazole derivative, commonly used as an impurity in the production of albendazole and fenbendazole. This compound is characterized by its white to off-white crystalline appearance and has a molecular formula of C13H14N2O2S.

What are the main uses of Albendazole EP Impurity E (CAS: 10605-21-7)?

Albendazole EP Impurity E is primarily used in pharmaceutical quality control to identify and quantify impurities in albendazole and fenbendazole drugs. It may also be relevant in research settings for studying related compounds and their effects. Additionally, it is used in the chemical industry for the synthesis of other benzimidazole-based compounds and in food safety testing for trace analysis of veterinary drug residues.

Is Albendazole EP Impurity E (CAS: 10605-21-7) safe?

Albendazole EP Impurity E is generally considered safe when handled properly, but it should be treated with caution due to its potential toxicity. It is important to follow safety guidelines, use appropriate personal protective equipment (PPE), and ensure proper ventilation during handling. Regulatory standards emphasize the need for controlled exposure and safe disposal to minimize health and environmental risks.

How should Albendazole EP Impurity E (CAS: 10605-21-7) be stored?

Albendazole EP Impurity E should be stored in a cool, dry, and dark place, away from sources of heat and moisture. It is recommended to keep it in a sealed container at a temperature below 25°C and maintain low humidity levels. Avoid exposure to direct sunlight and ensure proper ventilation to preserve its stability and purity over time.