L-Valyl-L-glutaminylglycyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-asparaginyl-L-alpha-aspartyl-L-lysine | CAS No. 106021-96-9

L-Valyl-L-glutaminylglycyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-asparaginyl-L-alpha-aspartyl-L-lysine

Basic Information

CAS Number

106021-96-9

Molecular Formula

C39H64N12O19

Molecular Weight

1005.01 g/mol

AD

Basic Physical Properties

CC(C)C(C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)O)N

InChI

InChI=1S/C39H64N12O19/c1-17(2)31(43)38(68)47-18(6-9-25(41)53)32(62)44-15-27(55)45-19(7-10-28(56)57)33(63)46-20(8-11-29(58)59)34(64)51-24(16-52)37(67)49-22(13-26(42)54)35(65)50-23(14-30(60)61)36(66)48-21(39(69)70)5-3-4-12-40/h17-24,31,52H,3-16,40,43H2,1-2H3,(H2,41,53)(H2,42,54)(H,44,62)(H,45,55)(H,46,63)(H,47,68)(H,48,66)(H,49,67)(H,50,65)(H,51,64)(H,56,57)(H,58,59)(H,60,61)(H,69,70)/t18-,19-,20-,21-,22-,23-,24-,31-/m0/s1

InChIKey

NIXBZDOQHRZFDR-OEWCNXHOSA-N

LogP

-7.969400000000004

Topological Polar Surface Area

540.4499999999998 Ų

Hydrogen Bond Donor/Acceptor

21 / 31

Complexity

1920

Synonyms & References

English

  • SCHEMBL6856783
  • HY-113893
  • Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys-OH
  • L-valyl-L-glutaminylglycyl-L-glutamyl-L-glutamyl-L-seryl-L-asparaginyl-L-aspartyl-L-lysine
  • -Interleukin I (163-171), human
  • interleukin-1beta (163-171)
  • 106021-96-9
  • Interleukin 1-beta (163-171)
  • NCGC00167209-01
  • (2S)-6-amino-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-5-amino-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-oxopentanoyl]amino]acetyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-hydroxypropanoyl]amino]-4-oxobutanoyl]amino]-3-carboxypropanoyl]amino]hexanoic acid
  • L-Lysine, N2-(N-(N2-(N-(N-(N-(N-(N2-L-valyl-L-glutaminyl)glycyl)-L-alph-glutamyl)-L-alpha-glutamyl)-L-seryl)-L-asparaginyl)-L-alpha-aspartyl)-
  • CS-0063273
  • IL-1beta (163-171)
  • H-Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys-OH
  • L-Lysine,l-valyl-L-glutaminylglycyl-L-a-glutamyl-L-a-glutamyl-L-seryl-L-asparaginyl-l-a-aspartyl-
  • L-Lysine,L-valyl-L-glutaminylglycyl-L-a-glutamyl-L-a-glutamyl-L-seryl-L-asparaginyl-L-a-aspartyl-
  • [beta]-Interleukin I (163-171), human
  • beta-Interleukin I (163-171), human
  • H-VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS-OH
  • IL-1β (163-171) (human)
  • IL-1β (163-171) (human), Interleukin-1β (163-171) (human)
  • L-Lysine,L-valyl-L-glutaminylglycyl-L-a-glutamyl-L-a-glutamyl-L-seryl-L-asparaginyl-L-a-aspart...
  • VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS
  • b-Interleukin I (163-171), human
  • IL-1B (163-171) (HUMAN)
  • IL-1BETA (163-171) (HUMAN)
  • INTERLEUKIN-1B (163-171) (HUMAN)
  • INTERLEUKIN-1BETA (163-171) (HUMAN)
  • β-INTERLEUKIN I (163-171), HUMAN
  • interleukin-1beta(163-171
  • interleukin-1β fragment 163-171 human

FAQ

What regulatory guidelines apply to L-Valyl-L-glutaminylglycyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-asparaginyl-L-alpha-aspartyl-L-lysine (CAS: 106021-96-9)?

L-Valyl-L-glutaminylglycyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-asparaginyl-L-alpha-aspartyl-L-lysine (CAS: 106021-96-9) is regulated under the Globally Harmonized System (GHS) of Classification and Labelling of Chemicals for hazards such as skin and eye irritation. Specific REACH regulations apply to its manufacturing and use in the European Union, requiring safety data sheets and substance registration. In the United States, FDA and EPA guidelines govern its handling and disposal, ensuring compliance with environmental and occupational health standards.

Are there alternatives to L-Valyl-L-glutaminylglycyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-asparaginyl-L-alpha-aspartyl-L-lysine (CAS: 106021-96-9) in synthesis?

For L-Valyl-L-glutaminylglycyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-asparaginyl-L-alpha-aspartyl-L-lysine (CAS: 106021-96-9), alternative reagents like similar dipeptides or tripeptides can be used in synthesis. Common substitutes include L-Valyl-L-glutamine and L-asparagine. However, these alternatives must be carefully selected to match the desired properties and functionality.

What is the market or research trend for L-Valyl-L-glutaminylglycyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-asparaginyl-L-alpha-aspartyl-L-lysine (CAS: 106021-96-9)?

The market for L-Valyl-L-glutaminylglycyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-asparaginyl-L-alpha-aspartyl-L-lysine (CAS: 106021-96-9) is driven by its applications in pharmaceuticals and research. Recent trends show an increase in demand for custom peptide synthesis services, particularly in areas like drug discovery and proteomics. Research is also focusing on its potential in biotechnology and biomedical applications, leading to emerging opportunities in the field.

How should waste containing L-Valyl-L-glutaminylglycyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-asparaginyl-L-alpha-aspartyl-L-lysine (CAS: 106021-96-9) be handled?

Waste containing L-Valyl-L-glutaminylglycyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-asparaginyl-L-alpha-aspartyl-L-lysine (CAS: 106021-96-9) should be collected in appropriate containers, then disposed of through professional waste disposal services. Incineration is a common method, but it must be conducted in accordance with environmental regulations. Alternative methods like chemical treatment or biological degradation can also be considered, depending on local regulations and the specific nature of the waste. Proper handling is crucial for environmental protection and safety.

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