7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (1:1) | CAS No. 105956-99-8

7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (1:1)

Basic Information

CAS Number

105956-99-8

Molecular Formula

C17H18Cl2FN3O3

Molecular Weight

402.25 g/mol

AD

Basic Physical Properties

Melting Point

162-168°C

C1CC1N2C=C(C(=O)C3=CC(=C(C(=C32)Cl)N4CCC(C4)N)F)C(=O)O.Cl

InChI

InChI=1S/C17H17ClFN3O3.ClH/c18-13-14-10(5-12(19)15(13)21-4-3-8(20)6-21)16(23)11(17(24)25)7-22(14)9-1-2-9;/h5,7-9H,1-4,6,20H2,(H,24,25);1H

InChIKey

BMACYHMTJHBPOX-UHFFFAOYSA-N

LogP

2.786300000000001

Topological Polar Surface Area

88.56 Ų

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

626

Synonyms & References

English

  • NSC 759859
  • 7-(3-Aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid--hydrogen chloride (1/1)
  • 105956-99-8
  • CI-960 HCl
  • 105956-99-8 (HCl)
  • CLINAFLOXACIN HYDROCHLORIDE [WHO-DD]
  • BMACYHMTJHBPOX-UHFFFAOYSA-N
  • 3-Quinolinecarboxylic acid, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, hydrochloride (1:1)
  • Clinafoxacin hydrochloride
  • CLINAFLOXACIN HYDROCHLORIDE [MI]
  • 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Hydrochloride
  • DTXSID70909839
  • FT-0665096
  • (+/-)-7-(3-AMINO-1-PYRROLIDINYL)-8-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACID, MONOHYDROCHLORIDE
  • CLINAFLOXACIN HYDROCHLORIDE [MART.]
  • CS-0012059
  • 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid monohydrochloride
  • BCP25186
  • UNII-G17M59V0FY
  • 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3carboxylic acid monohydrochloride
  • J-001509
  • G17M59V0FY
  • CHEMBL537626
  • 3-QUINOLINECARBOXYLIC ACID, 7-(3-AMINO-1-PYRROLIDINYL)-8-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-, MONOHYDROCHLORIDE, (+/-)-
  • Clinafoxacin HCl
  • Clinafloxacin (hydrochloride)
  • SCHEMBL193233
  • 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
  • CCG-213321
  • NSC759859
  • CI 960 HCl

MDL Number

MFCD03840545

FAQ

What is 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 105956-99-8)?

7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride, also known as JTT-501 (CAS: 105956-99-8), is a synthetic compound primarily used in the development of antiviral drugs. It is characterized by its unique chemical structure and potent antiviral activity against various viruses.

What are the main uses of 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 105956-99-8)?

The main use of 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 105956-99-8) is in the research and development of antiviral drugs, particularly for treating viral infections such as hepatitis B and C. It shows promising potential in clinical trials as an antiviral agent.

Is 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 105956-99-8) safe?

7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 105956-99-8) is generally considered safe when handled and used as directed. However, it is important to follow all safety guidelines, wear appropriate personal protective equipment, and avoid contact with skin and eyes. Proper ventilation should be ensured during handling.

How should 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 105956-99-8) be stored?

7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 105956-99-8) should be stored in a cool, dry place, away from direct sunlight and sources of heat. The container should be tightly sealed to prevent moisture and light exposure. It is recommended to store this compound at a temperature below 25°C and in a well-ventilated area to ensure optimal stability and safety.

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