2-Chloro-5-(chloromethyl)-1,3-thiazole

Basic Information

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CAS Number

105827-91-6

Molecular Formula

C4H3Cl2NS

Molecular Weight

168.05 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

35°C

Boiling Point

268.6°C at 760 mmHg

Refractive Index

1.571

SMILES

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C1=C(SC(=N1)Cl)CCl

InChI

InChI=1S/C4H3Cl2NS/c5-1-3-2-7-4(6)8-3/h2H,1H2

InChIKey

VRMUIVKEHJSADG-UHFFFAOYSA-N

LogP

2.5353000000000003

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

80.4

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H311 Toxic in contact with skin
Acute toxicity, dermal

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H341 Suspected of causing genetic defects
Germ cell mutagenicity

H411 Toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class 8 (6.1) Class 8 (6.1)

Synonyms & References

English

2-chloro-5-chloromethyl-1,3-thiazole
GEO-00665
105827-91-6
MFCD01073549
SB67323
5-chloromethyl-2-chloro-1,3-thiazole
2-Chloro-5-chloromethylthiazole, analytical standard
AKOS005256315
UNII-857BYZ5HZD
2-chloro-5-(chloromethyl)thiazole
2-chloro-5-chloromethyl thiazole
CS-W002731
2-chloro-5-(chloromethyl)-1,3-thiazole
NS00004597
2-Chloro-5-chloromethylthiazole
5-(chloromethyl)-2-chlorothiazole
DTXSID40376791
STR02200
A2007
AB08016
PyClU?Chlorodipyrrolidinocarbenium hexafluorophosphate
2-chloro-5-thiazolylmethylchloride
857BYZ5HZD
VRMUIVKEHJSADG-UHFFFAOYSA-N
C3295
EC 429-830-5
AC-1163
FT-0601078
2-chloro-5-chloromethyl-thiazole
EN300-62780
2-Chloro-5-thiazolylmethyl chloride

MDL Number

MFCD01073549

Customs Code

2934100090

FAQ

What is 2-Chloro-5-(chloromethyl)-1,3-thiazole (CAS: 105827-91-6)?

2-Chloro-5-(chloromethyl)-1,3-thiazole (CAS: 105827-91-6) is a synthetic organic compound with the chemical formula C4H3Cl2NS. It features a thiazole ring substituted with chlorine atoms at positions 2 and 5, and a chloromethyl group at position 5. This compound is known for its reactivity and is commonly used as an intermediate in pharmaceutical and chemical synthesis processes.

What are the main uses of 2-Chloro-5-(chloromethyl)-1,3-thiazole (CAS: 105827-91-6)?

2-Chloro-5-(chloromethyl)-1,3-thiazole (CAS: 105827-91-6) is primarily utilized in the pharmaceutical industry for synthesizing antimicrobial agents and agrochemicals. It also serves as a key component in research for developing novel drugs and industrial applications, such as pesticides and dyes, due to its functional group versatility and reactivity.

Is 2-Chloro-5-(chloromethyl)-1,3-thiazole (CAS: 105827-91-6) safe?

2-Chloro-5-(chloromethyl)-1,3-thiazole (CAS: 105827-91-6) requires careful handling due to potential toxicity. It may irritate skin, eyes, and respiratory systems, so proper safety measures like gloves, ventilation, and protective eyewear are essential. Always follow OSHA and EPA guidelines for exposure limits and storage safety to ensure safe use in laboratories and industrial settings.

How should 2-Chloro-5-(chloromethyl)-1,3-thiazole (CAS: 105827-91-6) be stored?

Store 2-Chloro-5-(chloromethyl)-1,3-thiazole (CAS: 105827-91-6) in a tightly sealed container in a cool, dry place (below 25°C), away from light and moisture. Maintain low humidity levels and ensure proper ventilation to prevent degradation. Avoid storing near incompatible materials to ensure stability and safety.