Tropisetron Hydrochloride

Basic Information

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CAS Number

105826-92-4

Molecular Formula

C17H21ClN2O2

Molecular Weight

320.82 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Powder

Melting Point

285°C(dec.)

Boiling Point

No data available

Water Solubility

Soluble in water

Flash Point

No data available

Solubility

H2O: >10mg/mL

Vapor Pressure

No data available

SMILES

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CN1C2CCC1CC(C2)OC(=O)C3=CNC4=CC=CC=C43.Cl

InChI

InChI=1S/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,18H,6-9H2,1H3;1H/t11-,12+,13+;

InChIKey

XIEGSJAEZIGKSA-LUNMCBQDSA-N

LogP

3.3717000000000015

Topological Polar Surface Area

45.33 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

400

Safety Information

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GHS Hazard Pictograms

H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

(1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride
TROPISETRON HYDROCHLORIDE [JAN]
TROPISETRON HYDROCHLORIDE [WHO-DD]
A19338Q2YO
NC00239
(3-endo,8-syn)-3-[(1H-indol-3-ylcarbonyl)oxy]-8-methyl-8-azoniabicyclo[3.2.1]octane chloride
endo-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride
TROPISETRON MONOHYDROCHLORIDE [MI]
HB2827
1H-Indole-3-carboxylic acid, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, monohydrochloride, endo-
CCG-100989
SCHEMBL669358
Novaban
Navoban (TN)
Tropisetron hydrochloride (JAN)
UNII-A19338Q2YO
Tropisetron hydrochloride
SCHEMBL133873
HY-B0020
CHEMBL4303202
SDZ-ICS-930
CHEBI:77570
NSC-759842
MLS001401385
105826-92-4
3-Tropanylindole-3-carboxylate hydrochloride
1.ALPHA.H,5.ALPHA.H-TROPAN-3.ALPHA.-YL INDOLE-3-CARBOXYLATE HYDROCHLORIDE
EN300-7366499
Tropisetron monohydrochloride
DTXSID50909756
AKOS015955967

MDL Number

MFCD02313825

FAQ

What is Tropisetron Hydrochloride (CAS: 105826-92-4)?

Tropisetron Hydrochloride (CAS: 105826-92-4) is a serotonin receptor antagonist used primarily in pharmaceutical applications. Its chemical formula is C17H21N3O2S·HCl, and it appears as a white crystalline powder. It is soluble in water and has a molecular weight of 398.91 g/mol. This compound is known for its antiemetic properties and is commonly prescribed to manage chemotherapy-induced nausea and vomiting.

What are the main uses of Tropisetron Hydrochloride (CAS: 105826-92-4)?

Tropisetron Hydrochloride (CAS: 105826-92-4) is mainly used as an antiemetic drug in oncology to prevent nausea and vomiting caused by chemotherapy. It is also utilized in veterinary medicine for treating gastrointestinal disorders. Additionally, it serves as a research compound for studying serotonin receptor interactions. Its applications span pharmaceutical, medical, and research fields.

Is Tropisetron Hydrochloride (CAS: 105826-92-4) safe?

Tropisetron Hydrochloride (CAS: 105826-92-4) is considered safe when used as directed, with a well-established toxicity profile. It is approved by the FDA and WHO for its pharmaceutical applications. Handling precautions include avoiding eye contact and inhalation, while proper storage ensures stability. Always consult healthcare professionals for safe usage and dosage guidelines.

How should Tropisetron Hydrochloride (CAS: 105826-92-4) be stored?

Tropisetron Hydrochloride (CAS: 105826-92-4) should be stored in a cool, dry place at 20-25°C (68-77°F) with humidity control. It requires protection from light and should be kept in a sealed, airtight container. Proper storage conditions ensure stability and efficacy, preventing degradation over time. Always follow manufacturer guidelines for storage.