Nateglinide | CAS No. 105816-04-4

Nateglinide

Basic Information

CAS Number

105816-04-4

Molecular Formula

C19H27NO3

Molecular Weight

317.43 g/mol

AD

Basic Physical Properties

Melting Point

137-141 ºC

Boiling Point

527.6 °C at 760 mmHg

Density

1.104

Flash Point

272.9 °C

Solubility

DMSO: >5mg/mL

Refractive Index

1.536

Specific Rotation

-9.4° (c=1,in methanol)

CC(C)C1CCC(CC1)C(=O)NC(CC2=CC=CC=C2)C(=O)O

InChI

InChI=1S/C19H27NO3/c1-13(2)15-8-10-16(11-9-15)18(21)20-17(19(22)23)12-14-6-4-3-5-7-14/h3-7,13,15-17H,8-12H2,1-2H3,(H,20,21)(H,22,23)/t15-,16-,17-/m1/s1

InChIKey

OELFLUMRDSZNSF-BRWVUGGUSA-N

LogP

3.2609000000000012

Topological Polar Surface Area

66.4 Ų

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

393

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Toxicity

LD50 orally in rats: >2.0 g/kg (Hasegawa)

Synonyms & References

English

  • N-[(trans-4-Isopropylcyclohexyl)carbonyl]-D-phenylalanine
  • AB00639979-08
  • BIDD:GT0257
  • NATEGLINIDE [USP MONOGRAPH]
  • NATEGLINIDE [USAN]
  • A 4166
  • YM-026
  • Z1514053266
  • (R)-2-rel-((1r,4R)-4-Isopropylcyclohexanecarboxamido)-3-phenylpropanoicacid
  • D-Phenylalanine, N-((4-(1-methylethyl)cyclohexyl)carbonyl)-, cis-
  • SCHEMBL9232138
  • 105746-37-0
  • AB00639979-11
  • (2R)-2-[[oxo-(4-propan-2-ylcyclohexyl)methyl]amino]-3-phenylpropanoic acid
  • Nateglinide cis-isomer [USP]
  • DTXSID9040687
  • Nateglinide [USAN:USP:INN:BAN]
  • KS-5143
  • N-{[trans-4-(propan-2-yl)cyclohexyl]carbonyl}-D-phenylalanine
  • Starsis
  • {N}-[({TRANS}-4-ISOPROPYLCYCLOHEXYL)CARBONYL]-D-PHENYLALANINE
  • NCGC00271534-02
  • n-(trans-4-Isopropylcylolohexylcarboxyl)-d-phenylpropylicacid
  • NATEGLINIDE [USP-RS]
  • Q2254797
  • CHEMBL783
  • NCGC00271534-03
  • Nateglinide [INN]
  • SCHEMBL13753829
  • D-phenylalanine, N-((trans-4-(1-methylethyl)cyclohexyl)carbonyl)-
  • carboxamido)-3-phenylpropanoic acid

MDL Number

MFCD00875706

Customs Code

2924299090

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