(10S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide

Basic Information

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CAS Number

104746-04-5

Molecular Formula

C15H14N2O2

Molecular Weight

254.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

188-190°C

Boiling Point

431.275°C at 760 mmHg

Flash Point

214.628 °C

Refractive Index

1.677

SMILES

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C1C(C2=CC=CC=C2N(C3=CC=CC=C31)C(=O)N)O

InChI

InChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)/t14-/m0/s1

InChIKey

BMPDWHIDQYTSHX-AWEZNQCLSA-N

LogP

2.4929000000000006

Topological Polar Surface Area

66.56 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

347

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(10S)-10-Hydroxy-10,11-dihydro-5H-dibenzo(b,f)azepin-5-carboxamide
S(+)-Liscarbazepine
(S)-(+)-10,11-DIHYDRO-10-HYDROXY-5H-DIBENZ(B,F)AZEPINE-5-CARBOXAMIDE
DB14575
CHEBI:174358
(S)-(+)-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
Eslicarbazepine (USAN/INN)
SCHEMBL418933
DTXSID901316900
(S)-10-Monohydroxy-10,11-dihydro Carbamazepine (Eslicarbazepine)
(10S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
5H-Dibenz[b,f]azepine-5-carboxamide,10,11-dihydro-10-hydroxy-,(10S)-
ESLICARBAZEPINE (MART.)
(5S)-5-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide
Eslicarbazepina
104746-04-5
NS00077922
(S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
ESLICARBAZEPINE [WHO-DD]
EC 810-248-9
S-licarbazepine
5H-DIBENZ(B,F)AZEPINE-5-CARBOXAMIDE, 10,11-DIHYDRO-10-HYDROXY-, (10S)-
S-(+)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
J-001242
(9S)-9-hydroxy-2-azatricyclo[9.4.0.0,3,8]pentadeca-1(15),3,5,7,11,13-hexaene-2-carboxamide
BMPDWHIDQYTSHX-AWEZNQCLSA-N
HY-114703
(10S)-10,11-Dihydro-10-hydroxy-5H-dibenz(b,f)azepine-5-carboxamide
S-10-Monohydroxy-dihydro-carbamazepin
BIA-2194
(S)-MHD

MDL Number

MFCD08460933

Customs Code

2933990090

FAQ

What is (10S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide (CAS: 104746-04-5)?

(10S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide (CAS: 104746-04-5) is a complex organic compound. It has a molecular formula of C17H18N2O2 and exhibits unique physical properties such as a melting point of 180-182°C. This compound is notable for its structural complexity and potential applications in pharmaceuticals and research.

What are the main uses of (10S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide (CAS: 104746-04-5)?

(10S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide (CAS: 104746-04-5) is primarily used in pharmaceutical research for developing new drug candidates. It has shown potential in the study of neurological and inflammatory conditions. In industry, it may be used as a precursor in the synthesis of other compounds with pharmaceutical or chemical applications.

Is (10S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide (CAS: 104746-04-5) safe?

(10S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide (CAS: 104746-04-5) is generally considered safe for research use when handled with appropriate precautions. It is important to follow standard laboratory safety protocols, including the use of gloves and safety goggles. Storage away from heat and light is recommended to maintain its stability.

How should (10S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide (CAS: 104746-04-5) be stored?

(10S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide (CAS: 104746-04-5) should be stored in a cool, dry place away from direct sunlight and heat sources to maintain its stability. It is advisable to store it in a tightly sealed container to prevent exposure to moisture and air. Proper labeling and documentation of its storage conditions are also recommended.