(3R)-1-Methyl-3-pyrrolidinol

Basic Information

View in Editor

CAS Number

104641-60-3

Molecular Formula

C5H11NO

Molecular Weight

101.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Liquid

Boiling Point

106°C/35mmHg

Refractive Index

n20/D 1.4640(lit.)

Specific Rotation

-7 º (c=1%, chloroform)

SMILES

View in Editor

CN1CCC(C1)O

InChI

InChI=1S/C5H11NO/c1-6-3-2-5(7)4-6/h5,7H,2-4H2,1H3/t5-/m1/s1

InChIKey

FLVFPAIGVBQGET-RXMQYKEDSA-N

LogP

-0.3172000000000001

Topological Polar Surface Area

23.47 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

65.1

Safety Information

View Safety Information

GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Air Sensitive & Hygroscopic

Synonyms & References

English

AMY6896
BP-12650
A1924
(R)-(-)-METHYL-3-PYRROLIDINOL
(R)-(-)-1-Methyl-3-pyrrolidinol, 97%
3-Pyrrolidinol, 1-methyl-, (R)-
(R)-3-Hydroxy-1-methyl-pyrrolidine
(-)-1-methyl-3-pyrrolidinol
AS-16012
(R)-3-Hydroxy-1-methylpyrrolidine
FLVFPAIGVBQGET-RXMQYKEDSA-N
Q27264932
(R)-1-Methyl-3-pyrrolidinol
DTXSID30426239
MFCD03788747
(R)-3-hydroxy-1-methyl pyrrolidine
(R)-1-methylpyrrolidin-3-ol;(R)-3-Hydroxy-1-methylpyrrolidine
(3r)-1-methyl-3-pyrrolidinol
104641-60-3
(R)-(-)-1-Methyl-3-pyrrolidinol
1-Methyl-3-pyrrolidinol, (R)-
1-Methyl-3-pyrrolidinol, (-)-
AKOS012535883
(R)-1-Methyl-pyrrolidin-3-ol
SCHEMBL133294
3-Pyrrolidinol, 1-methyl-, (3R)-
F8884-9837
M1937
AKOS015850699
AC-6781
CS-W013705

MDL Number

MFCD03788747

FAQ

What are the physical and chemical properties of (3R)-1-Methyl-3-pyrrolidinol (CAS: 104641-60-3)?

(3R)-1-Methyl-3-pyrrolidinol (CAS: 104641-60-3) is a colorless to light yellow liquid with a molecular weight of approximately 113.16 g/mol. It is moderately soluble in water and highly soluble in ethanol and other polar solvents. This compound is known for its basic nature and can readily react with acids. It is often used in pharmaceuticals and other applications requiring its specific reactivity.

How is (3R)-1-Methyl-3-pyrrolidinol (CAS: 104641-60-3) typically synthesized?

(3R)-1-Methyl-3-pyrrolidinol (CAS: 104641-60-3) can be synthesized through the reduction of (3R)-1-methyl-3-pyrrolidone with sodium borohydride or similar reducing agents. The reaction typically yields a high selectivity and good yield, making it a common method in organic synthesis. This process is often carried out under mild conditions to ensure product purity.

What industries use (3R)-1-Methyl-3-pyrrolidinol (CAS: 104641-60-3)?

(3R)-1-Methyl-3-pyrrolidinol (CAS: 104641-60-3) is widely used in the pharmaceutical industry for its role as a chiral auxiliary. It is also utilized in the production of polymers, where its properties enhance the performance of certain materials. Additionally, it has applications in sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling (3R)-1-Methyl-3-pyrrolidinol (CAS: 104641-60-3)?

When handling (3R)-1-Methyl-3-pyrrolidinol (CAS: 104641-60-3), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed instructions and emergency procedures.