Bisoprolol hemifumarate

Basic Information

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CAS Number

104344-23-2

Molecular Formula

C40H66N2O12

Molecular Weight

766.97 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

99-105°C

Boiling Point

445°C at 760 mmHg

Density

1.033

Flash Point

222.9 °C

Solubility

DMSO: >20 mg/mL

Vapor Pressure

No data available

SMILES

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CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O.CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O.C(=CC(=O)O)C(=O)O

InChI

InChI=1S/2C18H31NO4.C4H4O4/c2*1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4;5-3(6)1-2-4(7)8/h2*5-8,14-15,17,19-20H,9-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+

InChIKey

VMDFASMUILANOL-WXXKFALUSA-N

LogP

4.443600000000004

Topological Polar Surface Area

194.5 Å²

Hydrogen Bond Donor/Acceptor

6 / 14

Complexity

397

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

Bisoprolol fumarate (USAN:USP:JAN)
CHEBI:3128
CAS-104344-23-2
Bisoprolol fumarate (JP17/USP)
ZIAC COMPONENT BISOPROLOL FUMARATE
(+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol fumarate (2:1) (salt)
DTXSID1045794
BISOPROLOL HEMIFUMARATE [MI]
BISOPROLOL FUMARATE [JAN]
2-PROPANOL, 1-(4-((2-(1-METHYLETHOXY)ETHOXY)METHYL)PHENOXY)-3-((1-METHYLETHYL)AMINO)-, (2E)-2-BUTENEDIOATE (2:1)
HMS3713A21
CL-297939
Biso-Puren
Emconcor
Fumarate, Bisoprolol
CCG-222255
Zebeta
BISOPROLOL FUMARATE (USP MONOGRAPH)
BISOPROLOL FUMARATE (USP-RS)
Zebeta (TN)
Bisoprolol hemifumarate- Bio-X
( inverted exclamation markA)-Bisoprolol hemifumarate
Tox21_500951
Bisomerck
Bisoprolol hemifumarate
HMS3675F20
1-(4-((2-isopropoxyethoxy)Methyl)phenoxy)-3-(isopropylaMino)propan-2-ol fuMarate;(+/-)-Bisoprolol Hemifumarate
104344-23-2
BISOPROLOL FUMARATE (MART.)
(+-)-1-(p-((2-Isopropoxyethoxy)methyl)phenoxy)-3-isopropylamino-2-propanol hemifumarate
BISOPROLOL FUMARATE [VANDF]

MDL Number

MFCD00673957

Customs Code

2933990090

FAQ

What is Bisoprolol hemifumarate (CAS: 104344-23-2)?

Bisoprolol hemifumarate is a selective beta-1 adrenergic receptor blocker, commonly used in cardiovascular medicine. Its chemical formula is C19H25NO4S·C4H6O4, and it is a white to off-white crystalline powder with good solubility in water. It is known for its stability and is often prescribed for hypertension and heart conditions.

What are the main uses of Bisoprolol hemifumarate (CAS: 104344-23-2)?

Bisoprolol hemifumarate is primarily used as a medication for treating high blood pressure (hypertension) and heart-related conditions such as angina and heart failure. It is also used in the management of arrhythmias. As a beta-blocker, it helps reduce heart rate and blood pressure, making it a key drug in cardiovascular therapy.

Is Bisoprolol hemifumarate (CAS: 104344-23-2) safe?

Bisoprolol hemifumarate is generally considered safe when used as directed. It is approved by regulatory authorities for its therapeutic applications. However, like all medications, it should be handled with care, and potential side effects or interactions should be discussed with a healthcare professional. Proper storage and usage are essential to maintain its safety and efficacy.

How should Bisoprolol hemifumarate (CAS: 104344-23-2) be stored?

Bisoprolol hemifumarate should be stored in a cool, dry place away from moisture and light. It is typically kept in a sealed container at a temperature between 15°C to 30°C. Avoid exposure to high humidity or extreme temperatures to ensure stability and prolong shelf life.