Peramivir trihydrate

Basic Information

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CAS Number

1041434-82-5

Molecular Formula

C15H34N4O7

Molecular Weight

382.46 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

257-262°C

SMILES

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CCC([C@@H]([C@H]1[C@H](NC(=N)N)C[C@@H]([C@H]1O)C(=O)O)NC(=O)C)CC.O.O.O

InChI

InChI=1S/C15H28N4O4.3H2O/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23;;;/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19);3*1H2/t9-,10+,11+,12-,13+;;;/m0.../s1

InChIKey

RFUCJKFZFXNIGB-ZBBHRWOZSA-N

LogP

-2.613529999999997

Topological Polar Surface Area

243.03 Å²

Hydrogen Bond Donor/Acceptor

13 / 11

Complexity

460

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Peramivir Trihydrate
BCX 1812 trihydrate
Rapiacta trihydrate
RWJ 270201 trihydrate
(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic acid hydrate
(1S,2S,3S,4R)-3-[(1S)-1-acetamido-2-ethylbutyl]-4-(diaminomethylideneamino)-2-hydroxycyclopentane-1-carboxylic acid,trihydrate
Peramivir
CS-0732
S-021812
eraMivir
PeraMivir Hydrate
BCX-1812,RWJ-270201
Peramivir Tirhydrate
Peramivir Impurity A
Rapiacta
RAPIVAB
BCX1812
BCX 1812
RWJ270201
RWJ 270201
9ZS94HQO3B
(1S,2S,3R,4R)-3-((S)-1-Acetamido-2-ethylbutyl)-4-guanidino-2-hydroxycyclopentanecarboxylic acid
3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID
BCZ
3-(1'-acetylamino-2'-ethyl)butyl-4-((aminoimino)methyl)amino-2-hydroxycyclopentane-1-carboxylic acid
3(R)-[1(S)-Acetamido-2-ethylbutyl]-4(R)-guanidino-2(S)-hy
Peramivir trihydrate

MDL Number

MFCD09837902

FAQ

What is Peramivir trihydrate (CAS: 1041434-82-5)?

Peramivir trihydrate (CAS: 1041434-82-5) is an antiviral medication used to treat influenza. Its chemical formula is C18H29N5O6·3H2O, and it exists as a white crystalline powder. It is soluble in water and has a molecular weight of 465.5 g/mol. The trihydrate form stabilizes the compound for pharmaceutical applications.

What are the main uses of Peramivir trihydrate (CAS: 1041434-82-5)?

Peramivir trihydrate (CAS: 1041434-82-5) is primarily used as an antiviral drug to treat acute uncomplicated influenza in adults and children. It functions as a neuraminidase inhibitor, preventing viral spread. Additionally, it is utilized in research for antiviral studies and in the production of pharmaceutical formulations for therapeutic purposes.

Is Peramivir trihydrate (CAS: 1041434-82-5) safe?

Peramivir trihydrate (CAS: 1041434-82-5) is considered safe when used as directed, with minimal toxicity in therapeutic doses. However, handling should follow standard laboratory safety protocols, including gloves and eye protection. It is approved by regulatory bodies like the FDA for medical use, but improper exposure may cause irritation. Always adhere to safety data sheet guidelines.

How should Peramivir trihydrate (CAS: 1041434-82-5) be stored?

Peramivir trihydrate (CAS: 1041434-82-5) should be stored in a cool, dry place at 2-8°C. Protect from light and moisture, and keep in airtight containers. Avoid exposure to incompatible substances. Proper storage ensures stability and efficacy, as recommended by pharmaceutical guidelines.