Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate | CAS No. 104085-30-5
Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate
Basic Information
CAS Number
104085-30-5
Molecular Formula
C13H15BrO4S
Molecular Weight
347.23 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
60-62°C
Safety Information
View Safety InformationHazard Class
Class IRRITANT
Class IRRITANT
Synonyms & References
English
- 1,3-diethyl 2-{[3-(bromomethyl)thiophen-2-yl]methylidene}propanedioate
- AKOS005070719
- DTXSID10377311
- 104085-30-5
- FT-0642555
- A800892
- diethyl 2-[[3-(bromomethyl)-2-thienyl]methylene]propanedioate
- Diethyl {[3-(bromomethyl)thiophen-2-yl]methylidene}propanedioate
- diethyl 2-{[3-(bromomethyl)-2-thienyl]methylene}malonate
- C13H15BrO4S
- MFCD00180836
- Diethyl 2-((3-(bromomethyl)thiophen-2-yl)methylene)malonate
- Diethyl 2-([3-(bromomethyl)-2-thienyl]methylene) malonate
- 6E-002
- diethyl 2-[[3-(bromomethyl)thiophen-2-yl]methylidene]propanedioate
- J-520263
- Diethyl 2-{[3-(bromomethyl)-2-thienyl]-methylene}malonate
- DIETHYL 2-{[3-(BROMOMETHYL)-2-THIENYL]-METHYLENE}MALONATE
- Propanedioic acid,2-[[3-(bromomethyl)-2-thienyl]methylene]-, 1,3-diethyl ester
- diethyl<<3-(bromomethyl)-2-thienyl>methylene>propanedioate
- DIETHYL 2-([3-(BROMOMETHYL)-2-THIENYL]METHYLENE)MALONATE
- Diethyl 2-((3-(bromomethyl)thiophen-2-yl)methylene)malonate
- Diethyl 2-{3-(Bromomethyl)-2-thienyl-methylene}malonate
MDL Number
MFCD00180836
Customs Code
2934999090
FAQ
What are the physical and chemical properties of Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate (CAS: 104085-30-5)?
Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate (CAS: 104085-30-5) is a crystalline compound with a molecular weight of around 342.14 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and acetone. It is moderately reactive and can undergo nucleophilic substitution reactions. The compound is stable under normal conditions but should be stored in a dry, cool place.
How is Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate (CAS: 104085-30-5) typically synthesized?
Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate can be synthesized through a multi-step process involving bromination and malonate esterification. Commonly, 2-bromothiophene and malonic acid diethyl ester are reacted in the presence of a base like triethylamine to form the desired product. The yield is typically around 70-80%, with good selectivity for the targeted esterification step.
What industries use Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate (CAS: 104085-30-5)?
Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate (CAS: 104085-30-5) is used in the pharmaceutical industry for intermediate synthesis and in the polymer industry for functional polymer modifications. It can also be utilized in sensor technology and semiconductor manufacturing for specific chemical functionalities.
What precautions should be taken when handling Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate (CAS: 104085-30-5)?
When handling Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate (CAS: 104085-30-5), it is important to use appropriate personal protective equipment (PPE) such as lab coats, gloves, and safety goggles. Work should be conducted in a well-ventilated fume hood to minimize inhalation risks. Spills should be cleaned up using absorbent materials and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.
Related Compounds
![8-Benzyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-8-azabicyclo[3.2.1]oct-2-ene structure](https://static.chemtradehub.com/structs/112/1123661-15-3-6f9d.webp "8-Benzyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-8-azabicyclo[3.2.1]oct-2-ene structure")
8-Benzyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-8-azabicyclo[3.2.1]oct-2-ene
CAS Number:
1123661-15-3
Molecular Formula:
C20H28BNO2
(2R)-2-Hydroxy-1-(2,4,5-trimethoxyphenyl)-1-propanone
CAS Number:
1229005-35-9
Molecular Formula:
C12H16O5
Methyl 4-fluoro-2-(methoxymethyl)-5-nitrobenzoate
CAS Number:
1243164-13-7
Molecular Formula:
C10H10FNO5
(2E)-2-Benzylidene-5-bromo-3-(cyclohexylamino)-1-indanone
CAS Number:
1245792-67-9
Molecular Formula:
C22H22BrNO
Methyl 4-((tert-butoxycarbonyl)amino)piperidine-4-carboxylate hydrochloride
CAS Number:
1381947-68-7
Molecular Formula:
C12H23ClN2O4
You might also like
Compound Q&A
What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?
6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...
21889-89-46-Methyl-7-oxabicycl...
Compound Q&A
What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?
4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...
906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A
What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?
2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...
49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A
What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?
2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...
24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A
What is 2-Oxopropanamide (CAS: 631-66-3)?
2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...
631-66-32-Oxopropanamide
Compound Q&A
What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?
2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...
1289040-88-52-Methyl-2-propanyl ...
Compound Q&A
What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?
NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...
2241019-57-6NAMPT inhibitor-link...
Compound Q&A
What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?
It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...
1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A
What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?
1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...
794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A
What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?
Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...
1314981-48-0Vinyl(chloromethyl)d...
![Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate — Jin Jinle (Hunan) Chemical Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce76192b2de6e8e95a464e/67ce76192b2de6e8e95a464e-logo.webp){kind=logo}
![Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate — Shanghai Jixiang Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce6f4d2b2de6e8e95a45bf/67ce6f4d2b2de6e8e95a45bf-logo.webp){kind=logo}
![Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate — Hubei Yangxin Pharmaceutical Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67cded3957537e5c8069af88/67cded3957537e5c8069af88-logo.webp){kind=logo}
![Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate — JiangSuAiKangShengWuYiYaoYanFa Co Ltd](https://static.chemtradehub.com/suppliers/67cec9452b2de6e8e95a52fa/67cec9452b2de6e8e95a52fa-logo.webp){kind=logo}
![Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate — ShenZhenAiTaHuaXue Co Ltd](https://static.chemtradehub.com/suppliers/67ced0fb2b2de6e8e95a67fa/67ced0fb2b2de6e8e95a67fa-logo.webp){kind=logo}
![Diethyl {[3-(bromomethyl)-2-thienyl]methylene}malonate — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}