Atipamezole HCl

Basic Information

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CAS Number

104075-48-1

Molecular Formula

C14H17ClN2

Molecular Weight

248.76 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

No data available

Melting Point

218.0 to 222.0 deg-C

Boiling Point

396℃ at 760 mmHg

Density

1.115

Flash Point

No data available

Vapor Pressure

No data available

SMILES

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CCC1(CC2=CC=CC=C2C1)C3=CN=CN3.Cl

InChI

InChI=1S/C14H16N2.ClH/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14;/h3-6,9-10H,2,7-8H2,1H3,(H,15,16);1H

InChIKey

PCCVCJAQMHDWJY-UHFFFAOYSA-N

LogP

3.2781000000000016

Topological Polar Surface Area

28.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

237

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Toxicity

LD50 in male, female rats (mg/kg): >50, 44 s.c. (Scheinin)

Synonyms & References

English

SY057281
MPV-1248 hydrochloride
AKOS025401424
5-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-1H-Imidazole hydrochloride
CHEMBL2361649
AMY10903
4-(2-Ethyl-2-indanyl)imidazole hydrochloride
SCHEMBL203964
ATIPAMEZOLE HYDROCHLORIDE (MART.)
NCGC00182707-02
Atipamezol Hydrochloride
PCCVCJAQMHDWJY-UHFFFAOYSA-N
BCP04113
HY-12380
BCP9000339
J-504668
AS-66133
MFCD06407819
2W4279571X
MPV 1248 hydrochloride
Atipamezole (hydrochloride)
Atipamezole HCl
DTXSID2048583
1H-Imidazole, 4-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-, monohydrochloride
DTXCID8028509
Atipamezole hydrochloride 100 microg/mL in Acetonitrile
CAS-104075-48-1
Atipamezolehydrochloride
Q27255684
ATIPAMEZOLE HYDROCHLORIDE [MI]
FT-0656606

MDL Number

MFCD06407819

Customs Code

2933290090

FAQ

What is Atipamezole HCl (CAS: 104075-48-1)?

Atipamezole HCl, also known as ATRX, is a veterinary drug used for the reversal of sedation and analgesia. It is a hydrochloride salt of atipamezole, a selective alpha-2 adrenoceptor antagonist. The chemical formula is C19H21NO4.HCl. It is a white or off-white crystalline powder with a bitter taste.

What are the main uses of Atipamezole HCl (CAS: 104075-48-1)?

Atipamezole HCl is primarily used in veterinary medicine for the reversal of sedation and analgesia induced by alpha-2 adrenergic receptor agonists such as xylazine. It is effective in both dogs and cats and is used to quickly recover animals from sedation in clinical and surgical settings.

Is Atipamezole HCl (CAS: 104075-48-1) safe?

Atipamezole HCl is generally considered safe when used according to the recommended dosages and protocols. However, it should be handled with care due to its potential to cause hypertension and tachycardia. Users should follow all safety guidelines, including wearing appropriate protective clothing and ensuring proper storage conditions. Toxicity data indicates that it is not acutely toxic, but it is important to avoid ingestion and contact with the skin or eyes.

How should Atipamezole HCl (CAS: 104075-48-1) be stored?

Atipamezole HCl should be stored in a tightly closed container at room temperature (15-30°C), away from direct sunlight and sources of heat. It should be kept dry and protected from moisture. Avoid freezing. Store in a cool, dry place, and keep out of reach of children and pets. It is recommended to store it in a locked cabinet if possible.