(S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one | CAS No. 1038924-65-0

(S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one

Basic Information

CAS Number

1038924-65-0

Molecular Formula

C22H25NO2

Molecular Weight

335.45 g/mol

AD

Basic Physical Properties

Solubility

Insuluble (8.1E-4 g/L) (25 ºC),

O=C1CC[C@H](N1C(=O)C(C)(C)C)Cc1ccc(cc1)c1ccccc1

InChI

InChI=1S/C22H25NO2/c1-22(2,3)21(25)23-19(13-14-20(23)24)15-16-9-11-18(12-10-16)17-7-5-4-6-8-17/h4-12,19H,13-15H2,1-3H3/t19-/m0/s1

InChIKey

KJBWLGPTOKGJSJ-IBGZPJMESA-N

LogP

4.459800000000004

Topological Polar Surface Area

37.38 Ų

Hydrogen Bond Donor/Acceptor

0 / 3

Synonyms & References

English

  • (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one
  • (S)-5-([1,1'-biphenyl]-4-ylmethyl)-1-pivaloylpyrrolidin-2-one
  • LCZ696 intermediate D
  • (S)-5-([1,1-Biphenyl]-4-ylmethyl)-1-pivaloylpyrrolidin-2-one

MDL Number

MFCD26401536

FAQ

What regulatory guidelines apply to (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one (CAS: 1038924-65-0)?

The (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one (CAS: 1038924-65-0) falls under the GHS regulations for classification and labeling of chemicals. It is also subject to the REACH regulations for registration, evaluation, authorization, and restriction of chemicals. FDA and EPA may require specific handling, storage, and disposal guidelines for this compound in the U.S. depending on its intended use.

Are there alternatives to (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one in synthesis?

There are several alternatives to (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one in synthesis, including the use of related compounds such as (R)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one or other biaryl derivatives. Common alternative reagents include different acids or esters that can be used as precursors in similar reactions.

What is the market or research trend for (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one?

The market and research trends for (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one (CAS: 1038924-65-0) are growing due to its applications in pharmaceuticals and organic synthesis. Recent research has focused on its potential in drug development and as a chiral building block. Market demand is expected to increase as more applications are discovered and developed.

How should waste containing (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one (CAS: 1038924-65-0) be handled?

Waste containing (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one (CAS: 1038924-65-0) should be collected and disposed of according to local and international regulations. It is recommended to use professional waste disposal services that adhere to proper incineration or chemical treatment methods. Environmental protection measures should include minimizing waste generation and ensuring all waste is adequately treated to prevent environmental contamination.

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