2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide

Basic Information

View in Editor

CAS Number

1038915-60-4

Molecular Formula

C19H20N4O

Molecular Weight

320.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

463.619°C at 760 mmHg

SMILES

View in Editor

NC(=O)c1cccc2cn(nc12)c3ccc(cc3)[C@@H]4CCCNC4

InChI

InChI=1S/C19H20N4O/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24)/t14-/m1/s1

InChIKey

PCHKPVIQAHNQLW-CQSZACIVSA-N

LogP

2.5914

Topological Polar Surface Area

72.94 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

449

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(S)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide
MK4827
MK-4827 (Niraparib)
(S)-2-(4-(piperidin-3-yl)phenyl)-2Hindazole-7-carboxamide
2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide
MK-4827
Niraparib
2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
4-Quinolinamine
7-chloro-N-[(3-chlorophenyl)[4-(1-pyrrolidinylmethyl)phenyl]methyl]-
CHEMBL1094636
Niraparib (USAN)
Niraparib [USAN]
pound notMK4827 pound not MK 4827
2-[4-((3S)-3-Piperidinyl)phenyl]-2H-indazole-7-carboxamide
EOS-60867
MK4827 (Niraparib)
Niraparib (MK-4827)
2-[4-(3S)piperidin-3-ylphenyl]-2H-indazol-7-carboxamide
2H-Indazole-7-carboxamide, 2-[4-(3S)-3-piperidinylphenyl]-
MK-4827,(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxaMide
(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide hydrocholoride
ZEJULA
HMC2H89N35
MK 4827
Niraparib [USAN:INN]
2-{4-[(3S)-piperidin-3-yl]phenyl}indazole-7-carboxamide
MK 4827 (Base)
Zejula (TN)
GTPL8275

MDL Number

MFCD17779309

FAQ

What is 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide (CAS: 1038915-60-4)?

2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide (CAS: 1038915-60-4) is a synthetic organic compound containing an indazole ring and a piperidine group. It is a white to off-white solid with molecular formula C19H21N3O2 and exhibits moderate solubility in polar solvents. This compound is known for its potential in pharmaceutical research due to its structural complexity and biological activity.

What are the main uses of 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide (CAS: 1038915-60-4)?

The primary application of 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide (CAS: 1038915-60-4) lies in pharmaceutical research, where it serves as an intermediate for developing drugs targeting inflammation, cancer, and neurodegenerative diseases. It is also used in medicinal chemistry for structure-activity relationship studies and as a building block in the synthesis of bioactive molecules.

Is 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide (CAS: 1038915-60-4) safe?

Safety of 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide (CAS: 1038915-60-4) depends on exposure conditions. It is generally considered low to moderately toxic, requiring proper handling to avoid skin and respiratory contact. Protective equipment, such as gloves and goggles, is recommended. Always follow safety guidelines for chemical exposure and consult safety data sheets for detailed information.

How should 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide (CAS: 1038915-60-4) be stored?

Store 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide (CAS: 1038915-60-4) in a cool, dry place (ideally 2-8°C), away from light and moisture. Keep in a sealed, airtight container to maintain stability. Avoid exposure to strong acids or bases, and ensure storage conditions prevent degradation. Always follow manufacturer guidelines for long-term preservation.

Related Compounds

1,3-Dibromo-2,4-dichloro-5-fluorobenzene structure

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...

Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...

Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...

Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...

Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide

Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...

Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...

Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...

Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...

Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...

2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide | CAS No. 1038915-60-4

Basic Information

CAS Number

Molecular Formula

Molecular Weight

Chemical Classification

Basic Physical Properties

Boiling Point

Chemical Properties

SMILES

InChI

InChIKey

LogP

Topological Polar Surface Area

Hydrogen Bond Donor/Acceptor

Complexity

Safety Information

Hazard Statement

Synonyms & References

English

MDL Number

FAQ

What is 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide (CAS: 1038915-60-4)?

What are the main uses of 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide (CAS: 1038915-60-4)?

Is 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide (CAS: 1038915-60-4) safe?

How should 2-{4-[(3S)-3-Piperidinyl]phenyl}-2H-indazole-7-carboxamide (CAS: 1038915-60-4) be stored?

Related Compounds

You might also like

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

What is 2-Oxopropanamide (CAS: 631-66-3)?

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Supplier Information

MedChemExpress LLC

ShangHaiJiZhiShengHua Technology Co Ltd

NuoHengYiYaoKeJi （ ShangHai ） Co Ltd

WuHanShuangJinJingXi Chemical Co Ltd

Hubei Tuopan Chemical Co., Ltd.

Shanghai Mofu Medicine Technology Co., Ltd.

Haoke Development Area Cuilibi Chemical Technology Co., Ltd.

Hubei Changao Pharmaceutical Co., Ltd.

HuBeiChangRunShengWuYiYaoJiShu Co Ltd

WuHanShiXingYiAiKeShengWuYiYao Co Ltd

Shandong Sihuan Pharmaceutical Co., Ltd.

Hubei Shixing Chemical Co., Ltd.

NaJingPuXinYiYao Technology Co Ltd

ShangHaiChuangSai Technology Co Ltd

TianMenHengChang Chemical Co Ltd

Product Inquiry