3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole

Basic Information

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CAS Number

1032452-86-0

Molecular Formula

C13H10ClN3

Molecular Weight

243.7 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

486.3±28.0°C at 760 mmHg

SMILES

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CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)Cl

InChI

InChI=1S/C13H10ClN3/c1-17-8-10(9-4-2-3-5-12(9)17)11-6-7-15-13(14)16-11/h2-8H,1H3

InChIKey

IIBWXYHPBMUNJP-UHFFFAOYSA-N

LogP

3.288700000000002

Topological Polar Surface Area

30.71 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

273

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H317 May cause an allergic skin reaction
Sensitization, Skin

Synonyms & References

English

3-(2-chloropyriMidin-4-yl)-1-Methyl-1H-indole
3-(2-Chloropyrimidin-4-yl)-1-methylindole
1H-Indole, 3-(2-chloro-4-pyrimidinyl)-1-methyl-
3-(2-Chloropyrimidin-4-yl)-1-meth ylindole
AZD9291Intermediate5
Osimertinib Inter
EOS-61220
elagolix intermediate 11
3-(2-Chloro-4-pyrimidinyl)-1-methyl-1H-indole
AK316674
3-(2-Chloro-4-pyrimidyl)-1-methylindole
IIBWXYHPBMUNJP-UHFFFAOYSA-N
SB15000
SY040537
3-(2-chloropyrimidin-4-yl)-1-methyl-indole
3-(2-chloro-pyrimidin-4-yl)-1-methyl-1H-indole
1H-Indole, 3-(2-chloro-4-pyrimidiny
3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole
MFCD26397861
DB-330624
Y10231
DS-11451
CS-B0929
3-(2-chloropyrimidin-4-yl)-1-methylindole
AC-30107
SCHEMBL5096322
AMY442
AKOS027250595
1032452-86-0

MDL Number

MFCD26397861

FAQ

What is 3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole (CAS: 1032452-86-0)?

3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole (CAS: 1032452-86-0) is an organic compound featuring a pyrimidine ring substituted with a chlorine atom at position 2 and a methyl group at position 1 of the indole ring. It exhibits aromatic properties and is commonly used as a synthetic intermediate in pharmaceutical research. The compound’s molecular formula is C13H10ClN3, and it appears as a solid at standard conditions.

What are the main uses of 3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole (CAS: 1032452-86-0)?

3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole (CAS: 1032452-86-0) is primarily utilized in pharmaceutical research for the development of drugs targeting metabolic disorders. It also serves as an intermediate in agrochemicals and materials science. Its unique chemical structure makes it valuable for synthesizing bioactive compounds and organic materials, though specific applications depend on further research and development.

Is 3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole (CAS: 1032452-86-0) safe?

Safety of 3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole (CAS: 1032452-86-0) is not well-documented, but general handling precautions apply. It is advisable to use protective equipment, such as gloves and goggles, and ensure proper ventilation during manipulation. As with many organic compounds, potential toxicity should be assessed through specific studies, and adherence to safety standards is recommended for its use in research settings.

How should 3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole (CAS: 1032452-86-0) be stored?

3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole (CAS: 1032452-86-0) should be stored in a cool, dry place, away from light, in a sealed container. It maintains stability under normal storage conditions but is sensitive to moisture and heat. Proper storage ensures its chemical integrity and minimizes risks associated with degradation or exposure.