6-Chloro-9H-purin-2-amine

Basic Information

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CAS Number

10310-21-1

Molecular Formula

C5H4ClN5

Molecular Weight

169.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Powder

Melting Point

>300 °C

Boiling Point

623.9°C at 760 mmHg

Water Solubility

1.7 g/L (20 ºC)

Flash Point

144.4℃

Solubility

Solubility in 1mol/L NaOH; very faint turbidity.

Refractive Index

1.6110 (estimate)

SMILES

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C1=NC2=C(N1)C(=NC(=N2)N)Cl

InChI

InChI=1S/C5H4ClN5/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H3,7,8,9,10,11)

InChIKey

RYYIULNRIVUMTQ-UHFFFAOYSA-N

LogP

0.5884999999999998

Topological Polar Surface Area

80.48 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

154

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Class KEEP COLD Class KEEP COLD

Synonyms & References

English

CHEBI:72345
1H-Purin-2-amine, 6-chloro-
AS-2051
CCRIS 3906
6-chloro-9h-purin-2-ylamine
6-CHLORO-9H-PURIN-2-YL-2-AMINE
FT-0600035
6-Chloro-7H-purin-2-ylamine
PD130981
SR-01000944797
CHEMBL226396
6GU
6-Chloro-2-purinamine
SR-01000944797-1
NSC-29570
133762-81-9
AKOS005622720
6-Chloroguanine
2-amino-6chloropurine
AB2611
NSC29570
NSC 29570
6-Chloro-2-purinamine, 6-Chloroguanine
6-chloro-2-amino-purine
SMR002529527
6-Cl-purine (1)
bmse000984
Purine, 2-amino-6-chloro-
6-Chloro-2-aminopurine
A15073
CS-D1374

MDL Number

MFCD00075252

Customs Code

2933990090

FAQ

What is 6-Chloro-9H-purin-2-amine (CAS: 10310-21-1)?

6-Chloro-9H-purin-2-amine is a purine derivative with the chemical formula C5H4ClN5. It features a chlorine atom at the 6-position and an amino group at the 2-position of the purine ring. This compound is typically a white solid with moderate solubility in polar solvents and exhibits basic properties due to the amino group. It is commonly used as an intermediate in organic synthesis and pharmaceutical research.

What are the main uses of 6-Chloro-9H-purin-2-amine (CAS: 10310-21-1)?

6-Chloro-9H-purin-2-amine finds applications in pharmaceuticals as a precursor for nucleoside analogs and antiviral agents. It is also utilized in industrial chemical synthesis and research for developing drugs targeting metabolic disorders. Its unique structure makes it valuable in the creation of bioactive molecules and as a component in dye and pigment formulations.

Is 6-Chloro-9H-purin-2-amine (CAS: 10310-21-1) safe?

6-Chloro-9H-purin-2-amine is classified as a hazardous chemical due to its potential to cause irritation and toxicity upon exposure. Safety precautions include wearing protective gloves, goggles, and ensuring proper ventilation. It should be handled in accordance with OSHA and EPA guidelines to minimize health and environmental risks. Always follow established safety protocols when working with this compound.

How should 6-Chloro-9H-purin-2-amine (CAS: 10310-21-1) be stored?

6-Chloro-9H-purin-2-amine should be stored in a cool, dry place away from light and moisture. Keep it in an airtight, corrosion-resistant container to maintain stability and prevent degradation. Avoid exposure to incompatible substances and ensure storage conditions comply with chemical safety standards to preserve its integrity.