Compound Q&A

How is Methyl 8-methylquinoline-7-carboxylate (CAS: 1030846-94-6) typically synthesized?

Answer

Methyl 8-methylquinoline-7-carboxylate
Methyl 8-methylquinoline-7-carboxylate (CAS: 1030846-94-6) is typically synthesized through the condensation of 8-methylquinoline-7-carboxylic acid with methyl alcohol, followed by esterification. This reaction is usually catalyzed by a strong acid such as sulfuric acid and proceeds under reflux conditions for a few hours. The product is isolated by recrystallization from an appropriate solvent, yielding a pure crystalline form with good yield and selectivity.

About

English Name Methyl 8-methylquinoline-7-carboxylate
Molecular Formula C12H11NO2
Molecular Weight 201.23 g/mol
SMILES CC1=C(C=CC2=C1N=CC=C2)C(=O)OC
InChIKey HYUFGCAJWJEANP-UHFFFAOYSA-N
Last Updated: 2026-01-01 15:34

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