3'-O-Methyladenosine

Basic Information

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CAS Number

10300-22-8

Molecular Formula

C11H15N5O4

Molecular Weight

281.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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COC1C(OC(C1O)N2C=NC3=C(N=CN=C32)N)CO

InChI

InChI=1S/C11H15N5O4/c1-19-8-5(2-17)20-11(7(8)18)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1

InChIKey

RYAFZRROCNNRFK-IOSLPCCCSA-N

LogP

-1.3258999999999996

Topological Polar Surface Area

128.54 Å²

Hydrogen Bond Donor/Acceptor

4 / 9

Complexity

349

Synonyms & References

English

NSC 103062
(2R,3R,4S,5R)-2-(6-Amino-purin-9-yl)-5-hydroxymethyl-4-methoxy-tetrahydro-furan-3-ol
(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-methoxy-tetrahydrofuran-3-ol
CHEMBL3142987
SCHEMBL3369124
AKOS027337553
10300-22-8
3'-O-methyl-Adenosine
CHEBI:165834
(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-methoxyoxolan-3-ol
Adenosine, 3'-O-methyl-
BS-50743
3'-o-methyl-d-adenosine
3'-O-Methyl adenosine
BP-58838
(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-methoxyoxolan-3-ol
MFCD00057003
(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol
F13609
3'-O-Methyladenosine
Adenosine, 3'-O-methyl-(7CI,8CI,9CI)
3’-O-METHYL-ADENOSINE
3'-OMe-A
3'-O-methyl-3'-deoxyadenosine
3'-O-Methyl-adenosin
3'-O-Methyl-D-adenosine
O3'-methyladenosine

MDL Number

MFCD00057003

FAQ

What regulatory guidelines apply to 3'-O-Methyladenosine (CAS: 10300-22-8)?

3'-O-Methyladenosine (CAS: 10300-22-8) falls under various regulatory guidelines such as GHS (Globally Harmonized System of Classification and Labeling of Chemicals) for classification and labeling, REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) for European manufacturers and importers, and FDA/EPA regulations for biocidal and pharmaceutical uses. It is important to consult the specific regulations and guidelines applicable in your region.

Are there alternatives to 3'-O-Methyladenosine (CAS: 10300-22-8) in synthesis?

Yes, there are several alternatives to 3'-O-Methyladenosine (CAS: 10300-22-8) in synthesis, including other nucleoside analogs such as 3'-Azido-Ade and 2'-Deoxy-3'-Azido-Ade. Common alternative reagents include methylating agents like dimethyl sulfate (DMS) and other chemical modifications that can be used to produce similar functional groups.

What is the market or research trend for 3'-O-Methyladenosine (CAS: 10300-22-8)?

The market for 3'-O-Methyladenosine (CAS: 10300-22-8) is growing due to its applications in RNA interference (RNAi) and gene therapy research. Recent research trends include its use as a therapeutic agent for treating viral infections and certain types of cancer. The demand for this compound is expected to increase as more studies validate its potential in these applications.

How should waste containing 3'-O-Methyladenosine (CAS: 10300-22-8) be handled?

Waste containing 3'-O-Methyladenosine (CAS: 10300-22-8) should be collected in appropriate containers and stored securely to prevent spills or leaks. It should be disposed of via incineration or professional waste disposal services that handle hazardous chemicals. Environmental protection precautions include proper labeling and documentation, as well as following local waste disposal regulations and guidelines.