Trelagliptin succinate

Basic Information

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CAS Number

1029877-94-8

Molecular Formula

C22H26FN5O6

Molecular Weight

135.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CN1C(=O)C=C(N(C1=O)CC2=C(C=CC(=C2)F)C#N)N3CCCC(C3)N.C(CC(=O)O)C(=O)O

InChI

InChI=1S/C18H20FN5O2.C4H6O4/c1-22-17(25)8-16(23-6-2-3-15(21)11-23)24(18(22)26)10-13-7-14(19)5-4-12(13)9-20;5-3(6)1-2-4(7)8/h4-5,7-8,15H,2-3,6,10-11,21H2,1H3;1-2H2,(H,5,6)(H,7,8)/t15-;/m1./s1

InChIKey

OGCNTTUPLQTBJI-XFULWGLBSA-N

LogP

0.09780000000000005

Topological Polar Surface Area

109.6 Å²

Hydrogen Bond Donor/Acceptor

5 / 5

Complexity

750

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

SRY-472
2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]-4-fluorobenzonitrile,butanedioic acid
SYR 472
SYR-472
Trelagliptin (succinate)
Trelagliptin succinat
Trelagliptin Succinate
Trelagliptin succinate(SYR 111472 succinate)
SureCN878010
SYR 111472 succinate
SYR-111472 Succinate
SYR472 succinate
SYR-472 succinate
Trelagliptin succinate - SYR 111472 succinate
Trelagliptin succinate [USAN]
Telagliptin Succinate
Trelagliptin Succinate API
SYR472
(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile succinate
2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]-4-fluorobenzonitrile;butanedioic acid
4118932Z90
SYR111472 SUCCINATE
AK198895
Zafatek (TN)
trelaglipti
zafatek
CHE
Trelagliptin succinate
(R)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile
succinate (1:1)
MFCD22665720

MDL Number

MFCD22665720

FAQ

What is Trelagliptin succinate (CAS: 1029877-94-8)?

Trelagliptin succinate (CAS: 1029877-94-8) is a pharmaceutical compound used as a DPP-4 inhibitor. It has the chemical formula C25H31N5O7S and is known for its stability in solid form. This compound is characterized by its role in enhancing glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) levels, making it effective for managing type 2 diabetes.

What are the main uses of Trelagliptin succinate (CAS: 1029877-94-8)?

Trelagliptin succinate (CAS: 1029877-94-8) is primarily used in pharmaceuticals to treat type 2 diabetes. As a DPP-4 inhibitor, it helps regulate blood sugar by prolonging the activity of incretin hormones. It is also utilized in research for studying metabolic disorders and in drug development for diabetes therapies.

Is Trelagliptin succinate (CAS: 1029877-94-8) safe?

Trelagliptin succinate (CAS: 1029877-94-8) is generally safe when used as directed, with minimal toxicity in therapeutic doses. Safety measures include avoiding misuse and following guidelines for handling during storage or synthesis. It meets pharmaceutical safety standards, but like all medications, it may cause side effects such as hypoglycemia or gastrointestinal issues in some patients.

How should Trelagliptin succinate (CAS: 1029877-94-8) be stored?

Trelagliptin succinate (CAS: 1029877-94-8) should be stored in a cool, dry place, away from direct light. Maintain temperature between 2-8°C (36-46°F) and protect from moisture by using airtight containers. Proper storage ensures stability and prevents degradation, adhering to pharmaceutical quality and safety protocols.