INTERMEDINE | CAS No. 10285-06-0

INTERMEDINE

Basic Information

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CAS Number

10285-06-0

Molecular Formula

C15H25NO5

Molecular Weight

299.37 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

SMILES

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CC(C)C(C(C)O)(C(=O)OCC1=CCN2C1C(CC2)O)O

InChI

InChI=1S/C15H25NO5/c1-9(2)15(20,10(3)17)14(19)21-8-11-4-6-16-7-5-12(18)13(11)16/h4,9-10,12-13,17-18,20H,5-8H2,1-3H3/t10-,12-,13-,15+/m1/s1

InChIKey

SFVVQRJOGUKCEG-OPQSFPLASA-N

LogP

-0.32729999999999965

Topological Polar Surface Area

90.23 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

436

Safety Information

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Hazard Class

Class 6.1(b) Class 6.1(b)

Synonyms & References

English

(2S,3R)-2,3-Dihydroxy-2-(1-methylethyl)butanoic Acid [(1R,7aR)-2,3,5,7a-Tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl]methyl Ester
((1R,7aR)-1-hydroxy-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl)methyl (2S,3R)-2,3-dihydroxy-2-isopropylbutanoate
(+)-Intermedine
Intermedine
Intermedina
Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, (2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, (1R-(1alpha,7(2S*,3R*),7abeta))-
1ST14165
CS-0062945
NS00067002
9-(+)-Trachelanthylretronecine
HY-113845
UNII-DLC9FEP81A
INTERMEDINE, (+)-
3'-EPI-LYCOPSAMINE
A902553
Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, [(1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl]methyl ester, (2S,3R)-; Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, (2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, [1R-[1?,7(2S*,3R*),7a?]]-; Intermedine (7CI,8CI); (+)-Intermedine; 3'-epi-Lycopsamine
[(7R,8R)-7-hydroxy-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl]methyl (2S)-2-hydroxy-2-[(1R)-1-hydroxyethyl]-3-methylbutanoate
SCHEMBL23464
BUTANOIC ACID, 2,3-DIHYDROXY-2-(1-METHYLETHYL)-, (2,3,5,7A-TETRAHYDRO-1-HYDROXY-1H-PYRROLIZIN-7-YL)METHYL ESTER, (1R-(1.ALPHA.,7(2S*,3R*),7A.BETA.))-
CHEBI:5941
Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, ((1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, (2S,3R)-
MS-24309
J-000818
Q27106936
[(1R,7aR)-1-hydroxy-2,3,5,7a-tetrahydro-1H-pyrrolo[1,2-a]pyrrol-7-yl]methyl (2S,3R)-2,3-dihydroxy-2-isopropylbutanoate
10285-06-0
Intermedine 100 microg/mL in Water
1414-01-3
Intermedinum
Intermedine, HPLC Grade
DTXSID001020073

MDL Number

MFCD09970420

FAQ

What are the physical and chemical properties of Intermedine (CAS: 10285-06-0)?

Intermedine (CAS: 10285-06-0) is a white crystalline solid with a molecular weight of approximately 194.17 g/mol. It has a solubility of 0.34 g/L in water and is slightly soluble in common organic solvents. Intermedine is moderately reactive towards bases and is stable towards light and air at room temperature.

How is Intermedine (CAS: 10285-06-0) typically synthesized?

Intermedine is typically synthesized via a multi-step process involving the condensation of 4-nitrophenol and 2-amino-3-pyridinecarbonitrile. The reaction requires a mild base catalyst and is conducted under mild conditions to achieve a yield of around 75%. The product is purified by recrystallization from ethanol.

What industries use Intermedine (CAS: 10285-06-0)?

Intermedine (CAS: 10285-06-0) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of certain drugs. It is also utilized in the polymer industry for its ability to modify properties of polymers, and in the electronics industry for its application in semiconductor materials and sensors.

What precautions should be taken when handling Intermedine (CAS: 10285-06-0)?

When handling Intermedine (CAS: 10285-06-0), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of dust or vapors. In case of a spill, it should be cleaned up using appropriate protocols, and the site should be decontaminated with water and detergent. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.