2-(Benzylamino)-2-methyl-1-propanol

Basic Information

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CAS Number

10250-27-8

Molecular Formula

C11H17NO

Molecular Weight

179.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

68-70 ºC

Boiling Point

300.8±17.0 ºC (760 Torr),

Flash Point

109.1±11.6 ºC,

SMILES

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CC(C)(CO)NCC1=CC=CC=C1

InChI

InChI=1S/C11H17NO/c1-11(2,9-13)12-8-10-6-4-3-5-7-10/h3-7,12-13H,8-9H2,1-2H3

InChIKey

JIDHEIXSIHNMCG-UHFFFAOYSA-N

LogP

1.5471000000000001

Topological Polar Surface Area

32.26 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

139

Synonyms & References

English

1-Propanol, 2-methyl-2-[(phenylmethyl)amino]-
DTXSID10359410
FT-0662675
SCHEMBL3631502
EN300-84762
MFCD04500950
AS-66622
2-BENZYLAMINO-2-METHYL-1-PROPANOL
2-(benzylamino)-2-methylpropan-1-ol
N-benzyl-2-amino-2-methyl-1-propanol
JIDHEIXSIHNMCG-UHFFFAOYSA-N
2-(benzylamino)-2-methyl-1-propanol
SB84242
Z57328799
2-(benzylamino)-2-methyl-propan-1-ol
J-000705
AKOS000285007
CS-0060978
AN-465/41988680
10250-27-8
2-(Benzylamino)-2-methylpropan-1-ol
2-Benzylamino-2-methyl-1-propanol
1-Propanol,2-methyl-2-[(phenylmethyl)amino]-
2-(benzylamino)-2-methyl-1-propanol(SALTDATA: HCl)
2-benzylamino-2-methyl-propan-1-ol
N-benzyl-2-amino-2-methylpropanol
(Benzyl)(2-hydroxy-1,1-dimethylethyl)amine
2-Methyl-2-[(phenylmethyl)amino]-1-propanol

MDL Number

MFCD04500950

Customs Code

2922199090

FAQ

What are the physical and chemical properties of 2-(Benzylamino)-2-methyl-1-propanol (CAS: 10250-27-8)?

2-(Benzylamino)-2-methyl-1-propanol (CAS: 10250-27-8) is a colorless liquid with a boiling point of 113-115°C and a molecular weight of 183.24 g/mol. It has a pKa of approximately 11 and is moderately soluble in water. This compound is reactive towards nucleophiles and exhibits basic properties due to the amino group.

How is 2-(Benzylamino)-2-methyl-1-propanol (CAS: 10250-27-8) typically synthesized?

2-(Benzylamino)-2-methyl-1-propanol is typically synthesized through multi-step reactions involving benzylamine and methyl acrylate. The process involves the condensation of benzylamine with methyl acrylate followed by reduction to form the desired alcohol. Common catalysts include palladium-based catalysts, and the overall yield is around 75-80%.

What industries use 2-(Benzylamino)-2-methyl-1-propanol (CAS: 10250-27-8)?

2-(Benzylamino)-2-methyl-1-propanol (CAS: 10250-27-8) is used in the pharmaceutical industry as a precursor in drug synthesis and in the polymer industry for the modification of polymers. It also finds applications in the sensor and semiconductor industries due to its functional groups, which provide opportunities for chemical modification and sensing properties.

What precautions should be taken when handling 2-(Benzylamino)-2-methyl-1-propanol (CAS: 10250-27-8)?

When handling 2-(Benzylamino)-2-methyl-1-propanol (CAS: 10250-27-8), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure that all handling is conducted in a fume hood to minimize exposure. Spills should be handled immediately with appropriate absorbents, and the area should be well-ventilated. Always refer to the safety data sheet (SDS) for specific handling and disposal instructions.