BOC-N-Me-THR-OH

Basic Information

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CAS Number

101759-72-2

Molecular Formula

C10H19NO5

Molecular Weight

233.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Boiling Point

360 ºC

Flash Point

171 ºC

SMILES

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CC(C(C(=O)O)N(C)C(=O)OC(C)(C)C)O

InChI

InChI=1S/C10H19NO5/c1-6(12)7(8(13)14)11(5)9(15)16-10(2,3)4/h6-7,12H,1-5H3,(H,13,14)/t6-,7+/m1/s1

InChIKey

NHXZARPGSOCYMJ-RQJHMYQMSA-N

LogP

0.6873000000000002

Topological Polar Surface Area

87.07000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

271

Synonyms & References

English

S11586
101759-72-2
Boc-MeThr-OH
BOC-N-ME-THR-OH
(2S,3R)-2-((tert-Butoxycarbonyl)(methyl)amino)-3-hydroxybutanoicacid
(2S,3R)-3-hydroxy-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]butanoic Acid
L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-
DTXSID20426687
AKOS015908219
SCHEMBL1486174
(2S,3R)-2-((tert-Butoxycarbonyl)(methyl)amino)-3-hydroxybutanoic acid
Boc-N-methyl-L-threonine
CS-0101240
N-(tert-Butoxycarbonyl)-N-methyl-L-threonine
MFCD02259477
HY-W048839
L-Threonine,N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-
(2S,3R)-3-hydroxy-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]butanoic acid
Boc-N-Me-Thr-OH
BOC-N-ME-THR-OH (BOC-N-METHYL-L-THREONINE)
Boc-Thr(Me)-OH
N-ALPHA-(T-BUTYLOXYCARBONYL)-N-ALPHA-METHYL-L-THREONINE
Boc-Thr(N-Me)-OH
X5878
BOC-L-METHR-OH
Boc-N-Me-L-Thr-OH
BOC-N-ME-THREONINE
N-BOC-N-METHYL-L-THREONINE
N-ALPHA-T-BUTOXYCARBONYL-N-METHYL-L-THREONINE
N-[(tert-Butoxy)carbonyl]-N-methyl-L-threonine

MDL Number

MFCD02259477

FAQ

What are the physical and chemical properties of BOC-N-Me-THR-OH (CAS: 101759-72-2)?

BOC-N-Me-THR-OH (CAS: 101759-72-2) is a crystalline compound with a molecular weight of approximately 361.43 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and DMSO. Chemically, it is stable under normal conditions but reacts with bases to form the deprotected product. It is often used in peptide chemistry and pharmaceutical research.

How is BOC-N-Me-THR-OH (CAS: 101759-72-2) typically synthesized?

BOC-N-Me-THR-OH (CAS: 101759-72-2) is typically synthesized by coupling N-Me-THR-OH with BOC-Cl using a suitable base like diisopropylethylamine (DIPEA) in an organic solvent. The reaction is conducted at room temperature, and the product is isolated by precipitation from a suitable solvent. The yield is generally high, and the method is well-established in peptide synthesis.

What industries use BOC-N-Me-THR-OH (CAS: 101759-72-2)?

BOC-N-Me-THR-OH (CAS: 101759-72-2) is primarily used in the pharmaceutical and biotechnology industries for the synthesis of peptides and proteins. It is also used in research and development for drug discovery and in the polymer and sensor industries for specific applications.

What precautions should be taken when handling BOC-N-Me-THR-OH (CAS: 101759-72-2)?

When handling BOC-N-Me-THR-OH (CAS: 101759-72-2), it is essential to wear appropriate personal protective equipment (PPE), such as gloves, goggles, and a laboratory coat. Work in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up immediately using appropriate solvents, and proper disposal methods should be followed. Always consult the Safety Data Sheet (SDS) for detailed safety information.