3-(4-Fluorophenyl)-2-methylpropionylchloride | CAS No. 1017183-70-8

3-(4-Fluorophenyl)-2-methylpropionylchloride

Basic Information

CAS Number

1017183-70-8

Molecular Formula

C10H10ClFO

Molecular Weight

200.64 g/mol

AD

Basic Physical Properties

Boiling Point

260.2±23.0 ºC (760 Torr),

Flash Point

111.2±22.6 ºC,

CC(CC1=CC=C(C=C1)F)C(=O)Cl

InChI

InChI=1S/C10H10ClFO/c1-7(10(11)13)6-8-2-4-9(12)5-3-8/h2-5,7H,6H2,1H3

InChIKey

HJOAOPVBPDCOFZ-UHFFFAOYSA-N

LogP

2.769700000000001

Topological Polar Surface Area

17.07 Ų

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

176

Synonyms & References

English

  • 3-(4-Fluorophenyl)-2-methylpropanoyl chloride
  • 3-(4-fluorophenyl)--2-Methylpropanoyl chloride
  • NS00077721
  • 3-(4-fluorophenyl)-2-methylpropanoylchloride
  • EC 426-370-7
  • 3-(4-FLUOROPHENYL)-2-METHYLPROPIONYLCHLORIDE
  • DTXSID30893609
  • MFCD09894790
  • AKOS015945847
  • 3-(4-fluorophenyl)-2-methylpropanoyl chloride
  • HJOAOPVBPDCOFZ-UHFFFAOYSA-N
  • 1017183-70-8
  • J-650238

MDL Number

MFCD09894790

FAQ

What regulatory guidelines apply to 3-(4-Fluorophenyl)-2-methylpropionylchloride (CAS: 1017183-70-8)?

The compound 3-(4-Fluorophenyl)-2-methylpropionylchloride (CAS: 1017183-70-8) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a hazardous chemical. It must comply with REACH regulations for registration, evaluation, authorization, and restriction of chemicals in the European Union. In the USA, it must adhere to FDA and EPA guidelines for chemical safety and environmental discharge. Laboratories handling this compound should follow specific safety data sheets (SDS) and ensure proper containment and disposal practices.

Are there alternatives to 3-(4-Fluorophenyl)-2-methylpropionylchloride (CAS: 1017183-70-8) in synthesis?

While 3-(4-Fluorophenyl)-2-methylpropionylchloride (CAS: 1017183-70-8) is a specific intermediate used in various organic syntheses, there are alternatives such as other chlorinated propionyl chlorides or substituted derivatives. Commonly, chemists use isomers or analogs like 2-(4-Fluorophenyl)-2-methylpropionyl chloride as viable substitutes. These alternatives may offer similar functionality but with different reactivity and solubility characteristics.

What is the market or research trend for 3-(4-Fluorophenyl)-2-methylpropionylchloride (CAS: 1017183-70-8)?

The market for 3-(4-Fluorophenyl)-2-methylpropionylchloride (CAS: 1017183-70-8) is primarily driven by its use in pharmaceutical and fine chemical industries. Research trends indicate increasing demand in drug synthesis, particularly for developing molecules with specific fluorine-containing functionalities. Price trends show fluctuations related to supply and demand dynamics. Emerging research fields include the exploration of its use in novel drug discovery and synthetic methodologies.

How should waste containing 3-(4-Fluorophenyl)-2-methylpropionylchloride (CAS: 1017183-70-8) be handled?

Waste containing 3-(4-Fluorophenyl)-2-methylpropionylchloride (CAS: 1017183-70-8) should be collected in appropriate containers and stored in a well-ventilated area. Proper incineration or professional waste disposal services are recommended to handle this hazardous chemical safely. Environmental precautions include ensuring no release into the atmosphere or water systems. Laboratories should follow strict waste management protocols and adhere to local environmental regulations to prevent contamination and ensure compliance.

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