2-Methyl-2-propanyl [(1R,2R)-2-aminocyclopentyl]carbamate | CAS No. 1016971-66-6

2-Methyl-2-propanyl [(1R,2R)-2-aminocyclopentyl]carbamate

Basic Information

CAS Number

1016971-66-6

Molecular Formula

C10H20N2O2

Molecular Weight

200.28 g/mol

AD

Basic Physical Properties

CC(C)(C)OC(=O)NC1CCCC1N

InChI

InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-8-6-4-5-7(8)11/h7-8H,4-6,11H2,1-3H3,(H,12,13)/t7-,8-/m1/s1

InChIKey

PAXDIBGWURAVIH-HTQZYQBOSA-N

LogP

1.3909

Topological Polar Surface Area

64.35 Ų

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

211

Safety Information

View Safety Information

GHS Hazard Pictograms

H314H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Synonyms & References

English

  • MFCD12197287
  • MFCD11040591
  • CS-0368621
  • PAXDIBGWURAVIH-HTQZYQBOSA-N
  • J-524335
  • t-Butyl N-[trans-2-aminocyclopentyl]carbamate
  • (1R,2R)-1-(Boc-amino)-2-aminocyclopentane
  • (+/-)-trans-N-tert-Butoxycarbonyl-1,2-cyclopentanediamine
  • rel-tert-Butyl ((1R,2R)-2-aminocyclopentyl)carbamate
  • TRANS-TERT-BUTYL (2-AMINOCYCLOPENTYL)CARBAMATE
  • EN300-60057
  • AS-79593
  • trans-1-(Boc-amino)-2-aminocyclopentane
  • F8889-8691
  • J-000477
  • DTXSID80589247
  • tert-butyl (1R,2R)-2-aminocyclopentylcarbamate
  • (1R,2R)-Boc-1,2-diaminocyclopentane
  • CS-0187991
  • AT11486
  • F53311
  • trans-N-tert-Butoxycarbonyl-1,2-cyclopentanediamine
  • (+/-)-trans-N-tert-Butoxycarbonyl-1,2-cyclopentane-diamine
  • (1R,2R)-trans-N-Boc-1,2-cyclopentanediamine
  • SCHEMBL741725
  • tert-Butyl(1R*,2R*)-2-aminocyclopentylcarbamate
  • (1R,2R)-trans-N-Boc-1,2-cyclopentanediamine, 98%
  • (1R*,2R*)-2-aminocyclopentylcarbamic acid tert-butyl ester
  • EN300-244890
  • tert-Butyl (1R*,2R*)-2-aminocyclopentylcarbamate
  • 365996-21-0

MDL Number

MFCD11040591

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl [(1R,2R)-2-aminocyclopentyl]carbamate (CAS: 1016971-66-6)?

2-Methyl-2-propanyl [(1R,2R)-2-aminocyclopentyl]carbamate is a colorless to white crystalline solid with a molecular weight of approximately 213.34 g/mol. It has a high solubility in organic solvents like methanol and ethanol but is poorly soluble in water. This compound is known for its reactivity in nucleophilic substitution reactions and its ability to form stable amide bonds.

How is 2-Methyl-2-propanyl [(1R,2R)-2-aminocyclopentyl]carbamate (CAS: 1016971-66-6) typically synthesized?

2-Methyl-2-propanyl [(1R,2R)-2-aminocyclopentyl]carbamate is typically synthesized via a multistep process involving the reaction of 2-aminocyclopentanol with 2-methyl-2-propanoyl chloride under basic conditions. The reaction proceeds with high selectivity and yields up to 90% of the desired product.

What industries use 2-Methyl-2-propanyl [(1R,2R)-2-aminocyclopentyl]carbamate (CAS: 1016971-66-6)?

2-Methyl-2-propanyl [(1R,2R)-2-aminocyclopentyl]carbamate is used in the pharmaceutical industry for the synthesis of various medicinal compounds. It also finds applications in the sensor and semiconductor industries, where it is utilized as a precursor for functional materials.

What precautions should be taken when handling 2-Methyl-2-propanyl [(1R,2R)-2-aminocyclopentyl]carbamate (CAS: 1016971-66-6)?

When handling 2-Methyl-2-propanyl [(1R,2R)-2-aminocyclopentyl]carbamate, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or a fume hood to avoid inhalation of vapors. Spills should be handled using appropriate absorbents, and the area should be flushed with water. For more detailed safety information, refer to the safety data sheet (SDS).

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