6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one | CAS No. 1016636-76-2

6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one

Basic Information

CAS Number

1016636-76-2

Molecular Formula

C13H13BrClN3O

Molecular Weight

342.62 g/mol

AD

Basic Physical Properties

Cc1c(Br)c(=O)n(C2CCCC2)c3nc(Cl)ncc13

InChI

InChI=1S/C13H13BrClN3O/c1-7-9-6-16-13(15)17-11(9)18(12(19)10(7)14)8-4-2-3-5-8/h6,8H,2-5H2,1H3

InChIKey

HJQCAEDIUJXGCQ-UHFFFAOYSA-N

LogP

3.6309200000000024

Topological Polar Surface Area

47.78 Ų

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

422

Safety Information

View Safety Information

Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin
H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

  • 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
  • 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one
  • 2-Chloro-6,7-dimethoxyquinoxaline
  • 6-BROMO-2-CHLORO-8-CYCLOPENTYL-5-METHYL-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE
  • Palbociclib Intermediate3
  • PD0332991
  • Pyrido[2,3-d]pyrimidin-7(8H)-one,6-bromo-2-chloro-8-cyclopentyl-5-methyl
  • QC-4423
  • PALBOCICLIB-PB3
  • PALBOCI
  • Palbociclib Impurity I
  • 6-broMo-2-chloro-8-cyclopentyl-5-
  • 6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one
  • 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-on
  • 6-BroMo-2-chloro-8-cyclopentyl-5-Methyl-8H-pyrido[2,3-d]pyriMidin-7-one
  • Pyrido[2,3-d]pyriMidin-7(8H)-one, 6-broMo-2-chloro-8-cyclopentyl-5-Methyl-
  • 6-Bromo-2-chloro-8-cyclopentyl-5-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one
  • HJQCAEDIUJXGCQ-UHFFFAOYSA-N
  • C13H13BrClN3O
  • PD0332991 Isethiote
  • BCP09136
  • 0432AA
  • CM14179
  • SB17740
  • CM11095
  • SY058
  • 6-bromo-2-chloro-8-cyclopentyl-5-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one

MDL Number

MFCD13181208

Customs Code

2933990090

FAQ

What is 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (CAS: 1016636-76-2)?

6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (CAS: 1016636-76-2) is a heterocyclic compound containing a pyrido[2,3-d]pyrimidinone ring system with bromo, chloro, cyclopentyl, and methyl substituents. It is a solid at room temperature, typically insoluble in water but soluble in organic solvents. Its chemical structure makes it relevant in pharmaceutical and research applications due to its potential biological activity and reactivity.

What are the main uses of 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (CAS: 1016636-76-2)?

This compound is primarily used as a pharmaceutical intermediate in the development of drugs targeting specific biological pathways. Its unique structure also makes it valuable in research for studying chemical reactivity and in industrial processes for synthesizing complex molecules. Applications include medicinal chemistry, agrochemicals, and materials science, with potential roles in enzyme inhibition and molecular design.

Is 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (CAS: 1016636-76-2) safe?

Safety of 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (CAS: 1016636-76-2) depends on exposure conditions. It is considered hazardous due to its halogenated nature and should be handled with appropriate PPE, including gloves and goggles. Proper ventilation is required during use, and adherence to OSHA and REACH safety standards is recommended to minimize health and environmental risks.

How should 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (CAS: 1016636-76-2) be stored?

Store 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (CAS: 1016636-76-2) in a cool (≤25°C), dry, and dark environment to maintain stability. Use airtight containers to prevent moisture and light exposure, which may degrade the compound. Avoid storage near incompatible materials and ensure proper labeling for safe handling and disposal.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...