(2R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-piperidinecarboxylic acid

Basic Information

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CAS Number

101555-63-9

Molecular Formula

C21H21NO4

Molecular Weight

351.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

No data available

Melting Point

155.0 to 159.0 deg-C

Boiling Point

561.6℃/760mmHg

Density

1.293

Flash Point

No data available

Refractive Index

1.62

Vapor Pressure

No data available

Specific Rotation

+26° (c=1 in DMF)

SMILES

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C1CCN(C(C1)C(=O)O)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

InChI

InChI=1S/C21H21NO4/c23-20(24)19-11-5-6-12-22(19)21(25)26-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13H2,(H,23,24)/t19-/m1/s1

InChIKey

CKLAZLINARHOTG-LJQANCHMSA-N

LogP

3.8746000000000036

Topological Polar Surface Area

66.84 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

514

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

fmoc-d-piperidine-2-carboxylic acid
Fmoc-D-pipecolic acid;Fmoc-D-Pip-OH
EN300-1556223
DTXSID901314811
A800406
(d)-n-fmoc-pipecolic acid
N-Fmoc-D-pipecolic acid
fmoc-d-homopro-oh
1-[(9H-fluoren-9-ylmethoxy)carbonyl]piperidine-2-carboxylic acid
(R)-N-Fmoc-piperidine-2-carboxylic acid, 97%
2-[9H-fluoren-9-ylmethoxy(oxo)methyl]-2-piperidinecarboxylic acid
AO-710/25079003
101555-63-9
AS-15971
D-Fmoc-pipecolic acid
CS-W011864
fmoc-(r)-(+)-piperidine-2-carboxylic acid
Fmoc-D-Pip-OH
CCG-256525
1-Fmoc-D-pipecolic Acid
(2R)-1-{[(9H-FLUOREN-9-YL)METHOXY]CARBONYL}PIPERIDINE-2-CARBOXYLIC ACID
AKOS015837390
(r)-1-(((9h-fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid
(R)-N-Fmoc-piperidine-2-carboxylic acid
fmoc-d-pipecolic acid
fmoc-d-hopro-oh
J-000432
MFCD00235899
CKLAZLINARHOTG-LJQANCHMSA-N
(R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-piperidinecarboxylic Acid
SCHEMBL119365

MDL Number

MFCD00235899

Customs Code

2933399090

FAQ

What is (2R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-piperidinecarboxylic acid (CAS: 101555-63-9)?

(2R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-piperidinecarboxylic acid, also known as fluorenylmethoxycarbonyl piperidine-2-carboxylic acid, is a chemical compound used in pharmaceuticals and research. It features a fluorenylmethoxycarbonyl group attached to a piperidine ring. This compound is often used as a protecting group in organic synthesis and drug development.

What are the main uses of (2R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-piperidinecarboxylic acid (CAS: 101555-63-9)?

(2R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-piperidinecarboxylic acid (CAS: 101555-63-9) is primarily used in the pharmaceutical industry as a protecting group in organic synthesis. It is employed to protect the hydroxyl group of sugars and other functional groups during chemical reactions. In research, it serves as a valuable reagent for preparing complex molecules.

Is (2R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-piperidinecarboxylic acid (CAS: 101555-63-9) safe?

(2R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-piperidinecarboxylic acid (CAS: 101555-63-9) is safe under proper handling and storage conditions. However, it should be used with caution due to its potential to cause skin irritation. It is important to wear gloves and protective clothing when handling the compound. Ensure good ventilation and avoid contact with eyes and skin.

How should (2R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-piperidinecarboxylic acid (CAS: 101555-63-9) be stored?

(2R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-piperidinecarboxylic acid (CAS: 101555-63-9) should be stored at a temperature between 2°C and 8°C, away from direct sunlight and moisture. Store in a well-ventilated area and use airtight containers to prevent moisture absorption. It is recommended to keep it in a cool, dry place and to avoid exposure to heat and light to maintain its stability and purity.