Thiazol-5-ylmethyl ((1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl)carbamate | CAS No. 1010808-43-1

Thiazol-5-ylmethyl ((1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl)carbamate

Basic Information

CAS Number

1010808-43-1

Molecular Formula

C25H29N3O4S

Molecular Weight

467.59 g/mol

AD

Basic Physical Properties

CC(=O)NC(CC1=CC=CC=C1)CC(C(CC2=CC=CC=C2)NC(=O)OCC3=CN=CS3)O

InChI

InChI=1S/C25H29N3O4S/c1-18(29)27-21(12-19-8-4-2-5-9-19)14-24(30)23(13-20-10-6-3-7-11-20)28-25(31)32-16-22-15-26-17-33-22/h2-11,15,17,21,23-24,30H,12-14,16H2,1H3,(H,27,29)(H,28,31)/t21-,23-,24-/m0/s1

InChIKey

LGKRKMCCXYIVTI-XWGVYQGASA-N

LogP

3.4790000000000023

Topological Polar Surface Area

100.55000000000001 Ų

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

596

Synonyms & References

English

  • 1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate
  • 1,3-Thiazol-5-ylmeth
  • 1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-5-acetamido-3-hydroxy-1,6-diphenylhexan-2-yl]carbamate
  • Ritonavir USP IMpurity A
  • N-[(1S,2S,4S)-4-(AcetylaMino)-2-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]carbaMic Acid 5-ThiazolylMethyl Ester
  • thiazol-5-ylmethyl ((2S,3S,5S)-5-acetamido-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate
  • 1010808-43-1
  • (1,3-thiazol-5-yl)methyl N-[(2S,3S,5S)-5-acetamido-3-hydroxy-1,6-diphenylhexan-2-yl]carbamate
  • Q27270683
  • RITONAVIR IMPURITY, ACETAMIDOALCOHOL- [USP IMPURITY]
  • Carbamic acid, N-((1S,2S,4S)-4-(acetylamino)-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)-, 5-thiazolylmethyl ester
  • 8KV2H7R99M
  • Ritonavir impurity C [EP]
  • 1,3-THIAZOL-5-YLMETHYL N-[(2S,3S,5S)-5-ACETAMIDO-3-HYDROXY-1,6-DIPHENYLHEXAN-2-YL]CARBAMATE
  • DB-322665
  • DTXSID60143725
  • Thiazol-5-ylmethyl ((2S,3S,5S)-5-acetamido-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate
  • UNII-8KV2H7R99M
  • 1,3-Thiazol-5-ylmethyl N-((1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl)carbamate
  • Thiazol-5-ylmethyl ((1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl)carbamate
  • N-[(1S,2S,4S)-4-(Acetylamino)-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamic Acid 5-Thiazolylmethyl Ester
  • Ritonavir impurity, acetamidoalcohol- [USP]
  • RITONAVIR IMPURITY C [EP IMPURITY]
  • Carbamic acid, N-[(1S,2S,4S)-4-(acetylamino)-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-, 5-thiazolylmethyl ester; 1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate; 1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-(ac

MDL Number

MFCD28358831

FAQ

What are the physical and chemical properties of Thiazol-5-ylmethyl ((1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl)carbamate (CAS: 1010808-43-1)?

Thiazol-5-ylmethyl ((1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl)carbamate is a crystalline compound with a molecular weight of approximately 515.57 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and acetonitrile. The compound is known for its moderate reactivity, particularly in forming ester and amide bonds, and it is stable under normal storage conditions.

How is Thiazol-5-ylmethyl ((1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl)carbamate (CAS: 1010808-43-1) typically synthesized?

Thiazol-5-ylmethyl ((1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl)carbamate is synthesized through a multistep process involving acylation, amidation, and coupling reactions. Commonly, the synthesis involves the use of acetic anhydride as the acetylating agent, followed by coupling with thiazole-5-carbaldehyde. The reaction typically yields a high purity product with good selectivity and moderate to high yield.

What industries use Thiazol-5-ylmethyl ((1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl)carbamate (CAS: 1010808-43-1)?

Thiazol-5-ylmethyl ((1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl)carbamate finds applications in the pharmaceutical industry due to its potential as a bioactive compound. It may also be used in the development of sensors and semiconductors for its unique chemical structure and reactivity. Further research is ongoing to explore its use in polymers and other advanced materials.

What precautions should be taken when handling Thiazol-5-ylmethyl ((1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl)carbamate (CAS: 1010808-43-1)?

When handling Thiazol-5-ylmethyl ((1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl)carbamate, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risks. Ensure proper storage to maintain the integrity of the compound. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.

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