Levofloxacin Carboxylic Acid (Levofloxacin Difluoro Impurity)

Basic Information

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CAS Number

100986-89-8

Molecular Formula

C13H9F2NO4

Molecular Weight

281.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

>300 °C

Boiling Point

459.2°C at 760 mmHg

Density

1.6±0.1 g/cm3

Flash Point

231.5±28.7 °C

Refractive Index

1.635

Vapor Pressure

0.0±1.2 mmHg at 25°C

SMILES

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C[C@H]1COc2c(F)c(F)cc3c(=O)c(cn1c23)C(=O)O

InChI

InChI=1S/C13H9F2NO4/c1-5-4-20-12-9(15)8(14)2-6-10(12)16(5)3-7(11(6)17)13(18)19/h2-3,5H,4H2,1H3,(H,18,19)/t5-/m0/s1

InChIKey

NVKWWNNJFKZNJO-YFKPBYRVSA-N

LogP

1.9312999999999996

Topological Polar Surface Area

68.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

495

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(S)-9,10-Difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-(3S)-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
Levofloxacin acid
LEVOFLOXACIN Q-ACID
(S)-(-)-9,10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
Levofloxacin carboxylic acid
(S)-(?)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido-[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
Levofloxacin Carboxylic Acid (Levofloxacin Difluoro Impurity)
(S)-9,10,difluro-3-Methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid
Levofloxacin Related CoMpound B
(S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
Levofloxacin USP RC B
Levofloxacin Impurity 12
Levefluorocarboxylic Acid
LEVOFLUOROCARBOXYLIC ACID
Levofloxacin EP Impurity C
Levofloxacin Difluoro Carboxylic Acid
S(-)-9,10-DIFL-2,3-DIHYDRO-3-ME-7H-PYRI&
9,10-Difluoro-3(S)-methyl-7-oxo-2,3-dihyd
08GT8FY84E
Levofloxacin q-acid, (-)-

MDL Number

MFCD04039905

Customs Code

2934999090

FAQ

What is Levofloxacin Carboxylic Acid (CAS: 100986-89-8)?

Levofloxacin Carboxylic Acid, with the CAS number 100986-89-8, is a chemical compound that serves as a difluoro impurity in the synthesis of levofloxacin. It is a derivative of the fluoroquinolone class of antibiotics and has the molecular formula C17H18FN3O3. This compound is typically used in pharmaceutical research and quality control to identify and analyze impurities during drug manufacturing.

What are the main uses of Levofloxacin Carboxylic Acid (CAS: 100986-89-8)?

Levofloxacin Carboxylic Acid (CAS: 100986-89-8) is primarily used in pharmaceutical development as an impurity marker for levofloxacin. It helps in assessing the purity and safety of the final drug product. Additionally, it is employed in analytical chemistry for quality control testing and research purposes related to antibiotic synthesis and degradation studies.

Is Levofloxacin Carboxylic Acid (CAS: 100986-89-8) safe?

Levofloxacin Carboxylic Acid (CAS: 100986-89-8) is generally considered safe when handled properly in controlled environments. However, as a chemical compound, it should be treated with standard laboratory safety precautions. It is important to follow guidelines for safe handling, storage, and disposal to minimize any potential health or environmental risks.

How should Levofloxacin Carboxylic Acid (CAS: 100986-89-8) be stored?

Levofloxacin Carboxylic Acid (CAS: 100986-89-8) should be stored in a cool, dry, and dark place, preferably at 2-8°C. It is recommended to keep it in a sealed container to prevent moisture ingress and contamination. Avoid exposure to direct sunlight and ensure proper ventilation when handling this compound in a laboratory setting.