(2,2-Dimethyl-1,3-dioxolan-4-yl)methanol

Basic Information

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CAS Number

100-79-8

Molecular Formula

C6H12O3

Molecular Weight

132.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

-27℃

Boiling Point

80°C/12mmHg

Water Solubility

miscible

Solubility

172g/l soluble

Refractive Index

n20/D 1.434(lit.)

SMILES

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CC1(C)OCC(CO)O1

InChI

InChI=1S/C6H12O3/c1-6(2)8-4-5(3-7)9-6/h5,7H,3-4H2,1-2H3

InChIKey

RNVYQYLELCKWAN-UHFFFAOYSA-N

LogP

0.13020000000000004

Topological Polar Surface Area

38.69 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

101

Safety Information

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GHS Hazard Pictograms

H319

Hazard Statement

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

Sensitive to air

Toxicity

LD50 in rats (g/kg): 7 orally; 3 i.p. (Perez)

Synonyms & References

English

Solketal
(+/-)-2,2-Dimethyl-1,3-dioxolane-4-methanol~(+/-)-1,2-O-Isopropylideneglycerol
Acetone ketal of glycerine
DL-alpha,beta-Isopropylideneglycerol
2,2-dimethyl-1,3-dioxolan-4-ylmethanol
glycerol 1,2-isopropylidene ether
4-hydroxymethyl-2,2-dimethyl-1,3-dioxolan
1,2-Isopropylidene-rac-glycerol
(+,-)-2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane
(2,2-Dimethyl-1,3-dioxolan-4-yl)methanol
DL-1,2-Isopropylideneglycerol
2,2-Dimethyl-1,3-dioxolane-4-methanol
(+/-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
(R,S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL
(±)-2,2-Dimethyl-1,3-dioxolane-4-methanol
(±)-2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane
1,2-Isopropylideneglycerol
1,2-O-Isopropylideneglycerol
2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane
(+/-)-2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane
GIE
SOLKETAL(R)
(RS)-Solketal
isopropylidene
acetoneglycerol
Glycerolacetone
glycerolacetonide
Solketal ,98%
Solketal, 97+%
SOLKETAL
(2,2-dimethyl-1,3-dioxolan-4-yl)methanol

MDL Number

MFCD00063238

Customs Code

29329970

FAQ

What is (2,2-Dimethyl-1,3-dioxolan-4-yl)methanol (CAS: 100-79-8)?

(2,2-Dimethyl-1,3-dioxolan-4-yl)methanol, with CAS number 100-79-8, is an organic compound featuring a dioxolane ring substituted with two methyl groups and a methanol group. It is a colorless liquid with a slightly sweet odor, known for its solubility in water and common use as a protective group in organic synthesis. Its chemical formula is C6H14O3, and it exhibits stability under normal conditions.

What are the main uses of (2,2-Dimethyl-1,3-dioxolan-4-yl)methanol (CAS: 100-79-8)?

This compound is widely used in pharmaceuticals as a protecting group for alcohols during drug synthesis. It also serves in industrial applications as a solvent and in the production of polymers. In research, it is employed for its utility in organic reactions and functional group manipulation. Its versatility makes it valuable in chemical and material science studies.

Is (2,2-Dimethyl-1,3-dioxolan-4-yl)methanol (CAS: 100-79-8) safe?

(2,2-Dimethyl-1,3-dioxolan-4-yl)methanol is generally considered safe when handled according to standard chemical safety protocols. However, it may cause skin or eye irritation, so protective measures like gloves, goggles, and proper ventilation are recommended. Safety data sheets (SDS) classify it under specific hazard codes, emphasizing the need for caution during handling and storage.

How should (2,2-Dimethyl-1,3-dioxolan-4-yl)methanol (CAS: 100-79-8) be stored?

Store (2,2-Dimethyl-1,3-dioxolan-4-yl)methanol in a sealed, airtight container in a cool, dry place (ideally 0-25°C) away from light. Maintain low humidity to prevent degradation and avoid exposure to incompatible substances. Keep it in a well-ventilated area and ensure storage conditions comply with safety standards to maintain stability and prevent contamination.